In this paper, we build a mechanistic system to understand the relation between a reduction in human mobility and Covid-19 spread dynamics within New York City. To this end, we propose a multivariate compartmental model that jointly models smartphone mobility data and case counts during the first 90 days of the epidemic. Parameter calibration is achieved through the formulation of a general Bayesian hierarchical model to provide uncertainty quantification of resulting estimates. The open-source probabilistic programming language Stan is used for the requisite computation. Through sensitivity analysis and out-of-sample forecasting, we find our simple and interpretable model provides evidence that reductions in human mobility altered case dynamics.
翻译:在本文中,我们建立了一个机械系统,以了解减少人员流动与纽约市内Covid-19扩散动态之间的关系。为此,我们提议了一个多变的区际模型,在流行病头90天联合模拟智能手机流动数据和案件计数。通过制定通用贝叶斯分级模型,提供由此得出的估计数的不确定性量化,实现了参数校准。开放源代码概率编程语言斯坦用于必要的计算。通过敏感度分析和抽样预测,我们发现我们简单和可解释的模式提供了人类流动性减少的证据,改变了案件动态。