Multi-organ segmentation, which identifies and separates different organs in medical images, is a fundamental task in medical image analysis. Recently, the immense success of deep learning motivated its wide adoption in multi-organ segmentation tasks. However, due to expensive labor costs and expertise, the availability of multi-organ annotations is usually limited and hence poses a challenge in obtaining sufficient training data for deep learning-based methods. In this paper, we aim to address this issue by combining off-the-shelf single-organ segmentation models to develop a multi-organ segmentation model on the target dataset, which helps get rid of the dependence on annotated data for multi-organ segmentation. To this end, we propose a novel dual-stage method that consists of a Model Adaptation stage and a Model Ensemble stage. The first stage enhances the generalization of each off-the-shelf segmentation model on the target domain, while the second stage distills and integrates knowledge from multiple adapted single-organ segmentation models. Extensive experiments on four abdomen datasets demonstrate that our proposed method can effectively leverage off-the-shelf single-organ segmentation models to obtain a tailored model for multi-organ segmentation with high accuracy.
翻译:多器官分割是指在医学图像中识别和分离不同器官的基本任务,在医学图像分析中具有重要的意义。近年来,深度学习的巨大成功促进了其在多器官分割任务中的广泛应用。然而,由于昂贵的劳动力成本和专业技术的要求,多器官分割标注数据的可用性通常有限,因此在获取用于深度学习方法的足够训练数据方面存在挑战。在本文中,我们旨在通过将现成的单器官分割模型组合起来,在目标数据集上开发一个多器官分割模型,从而消除对多器官分割标注数据的依赖。为此,我们提出了一种新的双阶段方法,其中包括模型适应阶段和模型集成阶段。第一阶段增强了每个现成分割模型在目标领域上的通用性,而第二阶段将多个适应的单器官分割模型的知识融合在一起。在四个腹部数据集上的广泛实验表明,我们提出的方法可以有效地利用现成的单器官分割模型,获得高精度的定制多器官分割模型。