This paper examines how pharmaceutical Artificial Intelligence advancements may affect the development of new drugs in the coming years. The question was answered by reviewing a rich body of source material, including industry literature, research journals, AI studies, market reports, market projections, discussion papers, press releases, and organizations' websites. The paper argues that continued innovation in pharmaceutical AI will enable rapid development of safe and effective therapies for previously untreatable diseases. A series of major points support this conclusion: The pharmaceutical industry is in a significant productivity crisis today, and AI-enabled research methods can be directly applied to reduce the time and cost of drug discovery projects. The industry already reported results such as a 10-fold reduction in drug molecule discovery times. Numerous AI alliances between industry, governments, and academia enabled utilizing proprietary data and led to outcomes such as the largest molecule toxicity database to date or more than 200 drug safety predictive models. The momentum was recently increased by the involvement of tech giants combined with record rounds of funding. The long-term effects will range from safer and more effective therapies, through the diminished role of pharmaceutical patents, to large-scale collaboration and new business strategies oriented around currently untreatable diseases. The paper notes that while many reviewed resources seem to have overly optimistic future expectations, even a fraction of these developments would alleviate the productivity crisis. Finally, the paper concludes that the focus on pharmaceutical AI put the industry on a trajectory towards another significant disruption: open data sharing and collaboration.
翻译:本文探讨了制药人工智能的进步在未来几年中会如何影响新药物的发展。这个问题的答案是,通过审查丰富的原始材料,包括工业文献、研究期刊、AI研究、市场报告、市场预测、讨论文件、新闻稿和各组织网站等,对大量来源材料,包括工业文献、研究杂志、AI研究、AI研究、市场报告、市场预测、市场预测、讨论文件、新闻稿和各组织网站等进行了审查。论文认为,制药人工智能的继续创新将有助于迅速发展安全有效的治疗以前无法治愈的疾病的治疗方法。一系列要点支持这一结论:制药业目前正处于重大的生产力危机之中,可以直接应用由AI带动的研究方法来减少药物发现项目的时间和费用。该行业已经报告了诸如药物分子发现时间减少10倍等大量来源材料。工业界、政府和学术界之间的许多AI联盟利用了专利数据,并导致诸如迄今为止最大的分子毒性数据库或200多个药物安全预测模型等结果。最近由于技术巨头的参与和创纪录的几轮供资而加大了势头。长期影响包括更安全和更有效的治疗方法、药品专利作用的削弱、大规模合作和新的商业战略,甚至已经围绕目前令人无法乐观的兴奋的疾病走向发展趋势。文件指出,最终将研究将研究。