巯基环糊精修饰银微腔阵列的SERS效应及其在PCBs痕量检测中的应用

项目名称： 巯基环糊精修饰银微腔阵列的SERS效应及其在PCBs痕量检测中的应用

项目编号： No.51301162

项目类型： 青年科学基金项目

立项/批准年度： 2014

项目学科： 一般工业技术

项目作者： 许伟

作者单位： 中国科学院合肥物质科学研究院

项目金额： 25万元

中文摘要： 多氯联苯（PCBs）对于环境所造成的危害正在日益显现，针对PCBs的快速痕量检测正推动着相关学科方向的发展。基于贵金属纳米结构基底的表面增强拉曼（SERS）效应是痕量检测的重要手段之一，但实现快速痕量检测还需要从其信号强度、可重复性以及针对PCBs分子的捕获能力等方面对基底进行改进。本项目拟采用SERS手段，针对这些关键科学问题，以阳极氧化铝（AAO）为模板构筑孔径在十纳米以下的银微腔结构阵列，并通过腔体直径的调控来增强其SERS活性，获得高活性、高密度且均匀分布的"热点"群，并以巯基环糊精为媒介分子对基底表面进行选位修饰来进一步提高基底对PCBs分子的吸附效率，最终得到高精度的、对一种或多种PCBs分子具有选择性响应的SERS基底，实现对PCBs的快速痕量检测。项目的实施将为贵金属纳米体系SERS 活性的进一步提高提供科学依据，并为PCBs快速痕量检测的实现奠定实验基础。

中文关键词： 表面拉曼增强；贵金属复合纳米结构；持久性有机污染物；痕量检测；

英文摘要： The harm of Polychlorinated Biphenyls (PCBs)is progressively evident in the current environment. The detection of PCBs-series pollutants has become a focus of relavent researches.One of the promising methods is the detection using surface enhanced Raman scattering (SERS) of noble metal nanostructured substrates. However, it is still a grand challenge to improve the signal intensity, reproducibility and the incubation efficiency to achieve trace detection. This program is intended on realising the fast, trace SERS detection of PCBs. By the fabrication of periodical sub-10-nm Ag nanocavity arrays using template synthesis,densely arranged highly active "hot spots" were introduced into the SERS substrate. The variation trend of SERS factor with the variation of structure parameters is studied. Moreover, the enhanced incubation of the PCBs molecules is also explored by the selective surface modification of the substrate with Thiolated Cyclodextrin. This program is ultimately aimed on the fabrication of highly-effective,applicable and PCBs-targeted SERS substrate. The execution of this program will provide a scientific basis for improving the SERS activity of noble-metal nanoscale systems and set up the experimental foundation for the fast trace detection of PCBs-series pollutants.

英文关键词： SERS；Composite noble metal nanostructures；POPs；Ultrasensitive detection；