菌紫质分子二向色性的测量与菌紫质薄膜光致各向异性特性的提高

项目名称： 菌紫质分子二向色性的测量与菌紫质薄膜光致各向异性特性的提高

项目编号： No.61205127

项目类型： 青年科学基金项目

立项/批准年度： 2013

项目学科： 信息四处

项目作者： 门克内木乐

作者单位： 内蒙古大学

项目金额： 25万元

中文摘要： 由于细菌视紫红质（BR）分子的较强二向色性（Γ），使得BR薄膜具有光致各向异性（POA），包括单光子吸收（SPA）型和双光子吸收（TPA）型两种。有关它们国内外都侧重于其应用研究，基础研究部分还有待于加强。比如，对单个BR分子的Γ-SPA与Γ-TPA大小测量，及BR薄膜TPA-POA特性的提高方法等方面，国际上都还未见相关报道，但其意义重大。 本项目中，通过对不同激发条件下，BR薄膜中产生的SPA-POA和TPA-POA进行详细测量，获得最佳激发条件，并拟合出BR分子的Γ-SPA与Γ-TPA大小（其中对分子的二向色性、排列方向、光反应常数、M态寿命、激发光和探测光的偏振态、光强度空间分布以及Lambert-Beer定律等各种因素都将考虑到）。同时我们还推测在产生SPA-POA的条件下，再用脉冲激光激发BR薄膜，则可提高其TPA-POA特性，本项目中将从理论和实验上验证这一方法的可行性。

中文关键词： 细菌视紫红质；分子二向色性；单光子吸收；双光子吸收；各向异性提高

英文摘要： Because of the Bacteriorhodopsin (BR) molecular strong dichroism (Γ), the BR films show photoinduced optical anisotropy (POA) properties, including single-photon absorption photoinduced optical anisotropy(SPA-POA) and two-photon absorption photoinduced optical anisotropy (TPA-POA). The researches on them have focused on their applications, the basic researches on them are yet to be strengthened. For example, up to now no reports were found on the measurement of BR molecular Γ-SPA and Γ-TPA and on any method to improve TPA-POA property of BR films. But these are very important. In this project, the SPA-POA and TPA-POA of BR films under different excitation conditions will be measured in detail, from which the optimum excitation condition can be obtained. And from the theoretical fitting on the experimental curves, the BR molecular Γ-SPA and Γ-TPA will be obtained(In the fitting, the various factors such as the molecular dichroism, molecular arrangement, reaction constant, M-state life time, polarization states of the excitation lights and probe light, spatial distribution of the light intensities and the Lambert-Beer law et al. will all be considered). We also speculated that when the BR films with SPA-POA are excited by pulse laser, their TPA-POA will be improved. In this project, the feasibility of this method

英文关键词： Bacteriorhodopsin；molecular dichroism；single photon absorption；two photon absorption；improvement of anisotropy