项目名称: 微磁场下SPR可调的Au负载Fe3O4@SiO2纳米复合结构的可控组装及其SERS性能研究
项目编号: No.51502299
项目类型: 青年科学基金项目
立项/批准年度: 2016
项目学科: 一般工业技术
项目作者: 甘自保
作者单位: 中国科学院合肥物质科学研究院
项目金额: 21万元
中文摘要: 表面增强拉曼散射(SERS)作为一种高灵敏的分子检测技术在分析检测领域具有重要的应用前景。规则有序排列的活性基底是获得稳定、可重现SERS信号的关键。然而,对于颗粒型SERS基底,如何实现其规则有序排列依旧是SERS技术所面临的挑战。控制技术为此提供了一个可行的解决方案。本项目拟设计、制备表面等离子体共振(SPR)可调的Au负载超顺磁Fe3O4@SiO2复合结构SERS基底和集微线圈装置的检测池,利用主动的微磁控制技术实现基底的规则有序排列。通过模拟不同电流激励下微磁场的场强、空间分布情况和记录基底在相应条件下的组装行为,揭示超顺磁基底的组装规律,实现对超顺磁基底组装行为的规律性控制。以农残分子为例,研究组装结构的SERS敏感性,获得具有最佳SERS活性的组装参数,分析可能的增强机理,并评估其稳定性和重现性。本研究将为实现颗粒型SERS基底的稳定性、重现性和灵敏性提供技术和理论支持。
中文关键词: 表面增强拉曼散射;超顺磁;可控组装;Au纳米粒子
英文摘要: Surface enhanced Raman scattering (SERS) as a highly sensitive molecular detection technique has significant application in the field of analysis and detection. Stable and reproducible SERS signals have close connection with uniform and orderly arranged active substrates. However, for granular SERS substrates, how to achieve their uniform and ordered arrangement is still the bottleneck of SERS technology. Control technology provides a feasible solution for it. This project aims to design and synthesize the tunable surface plasmon resonance (SPR) Au-coated superparamagnetic Fe3O4@SiO2 nanocomposites as SERS substrates, detection cell integrated micro-coil device, and use active micro-magnetic control technology to achieve uniform and ordered arrangement of SERS substrates. In order to reveal the magnetic assembly mechanism and realize the regularity control of ordered assembly behavior, we will simulate the strength and spatial distribution of micro-magnetic field and record their assembly behaviors under different current excitation. We will take pesticide molecules as probes, research SERS sensitivity of assembly structures, achieve the optimal assembly parameters, analyze the possible Raman enhancement mechanism and evaluate their SERS stability and reproducibility. This project will provide technical and theoretical supports for the realization of SERS stability, reproducibility and sensitivity of the granular SERS substrates.
英文关键词: Surface enhanced Raman scattering ;Superparamagnetic;Controllable assembly;Au nanoparticles