复杂体系痕量有机物微萃取基础研究：器件设计和表面修饰

项目名称： 复杂体系痕量有机物微萃取基础研究：器件设计和表面修饰

项目编号： No.21275144

项目类型： 面上项目

立项/批准年度： 2013

项目学科： 数理科学和化学

项目作者： 吴大朋

作者单位： 中国科学院大连化学物理研究所

项目金额： 80万元

中文摘要： 本项目以复杂体系中痕量有机物快速稳定微萃取为目的，针对结果重现性差、萃取时间长两个基本问题，提炼出高稳定萃取界面和快速分子传质两个关键科学问题；优选膜微萃取体系，开展以下研究：（1）设计、制备萃取新器件，缩短分子传质距离，提高膜有效萃取面积，加快分子传质；（2）选择修饰膜表面，调节膜孔直径和表面化学性质，抑制样品溶液对膜界面的物理扰动和化学污染，提高界面选择性和稳定性；（3）筛选离子对试剂，提高可电离有机物的电膜萃取效率；（4）以环境水体中挥发性酚类、蔬菜果汁中农药残留、植物激素赤霉素为验证对象，结合色谱-质谱分离鉴定手段，发展气相液膜微萃取、液液两相膜微萃取、液液液三相膜微萃取技术，推进复杂体系痕量有机物快速稳定样品前处理方法的发展。其中分子传质过程、器件设计、表面化学的研究结果，将为其它样品前处理方法、膜科学的发展提供重要科学借鉴。

中文关键词： 固相微萃取；液相微萃取；萃取器件；萃取材料；表面修饰

英文摘要： This project focuses on the fast and reliable microextraction of trace organic compounds from complex samples, to effectively overcome the poor reproducibility and long extraction time in current methods. Stable extraction interface and accelerated molecule transfer are chosen as the two key research objectives. The membrane-based microextraction methods, such as headspace membrane-based liquid phase micro extraction (HF-LPME), hollow fiber-based liquid liquid microextraction (HF-LLME), hollow fiber-based liquid liquid liquid microextraction (HF-LLLME), are chosen as optimal research models. First, the membrane device will be re-designed, and it will be fabricated based on electrospinning techniques. The transfer resistance in membrane solvent and in extraction phases will be decreased, and the effective extraction surface area per extraction phase will be increased, so the microextraction will be accelerated. Second, the membrane surface will be modified selectively to tune the pore size and its chemical properties, so the flow impact and chemical interference from sample solution will be largely inhibited, and the selectivity of membrane extraction will be further enhanced. Third, ion pair reagents for ionized organic compounds will be screened and added into the membrane solvent, so their electro-membrane ext

英文关键词： solid phase microextraction；liquid phase microextraction；extraction device；extraction material；surface modification