动态局部超分辨率眼底立体成像系统机理研究

项目名称： 动态局部超分辨率眼底立体成像系统机理研究

项目编号： No.61471039

项目类型： 面上项目

立项/批准年度： 2015

项目学科： 无线电电子学、电信技术

项目作者： 常军

作者单位： 北京理工大学

项目金额： 83万元

中文摘要： 人类眼底分布着大量各种动静脉血管，眼底图谱是一项可作为研究、诊断的重要资料，可直接反映出青光眼、高血压、动脉硬化、风湿等疾病。因此，眼底成像技术不仅是眼科疾病诊断的重要依据，而且是判断身体其他疾病病情程度的重要检查手段。另外，小型化医疗设备的开发对于解决医疗设备下乡、贯彻三农工作的问题有重大意义，本课题的研究内容符合国家未来健康稳定发展的重大需求。 本课题提出一种新型、适用于不同人眼的动态超分辨率眼底立体成像方案，重点研究复合照明系统和局部超分辨立体成像系统的原理和像差校正方法。照明系统采用新型复合光，在满足对人眼大视场照明同时，通过使用液晶空间光调制器对系统进行局部动态照明；在成像光学系统中，充分考虑到人眼的不同光学特性以及人眼抖动产生的像移，使用数字自适应光学技术，将全视场内视场角的像差分段校正到可分辨眼底视觉细胞的水平，再通过后续图像处理，从而实现眼底局部超分辨率动态立体成像。

中文关键词： 局部超分辨率；复合照明；自适应光学；眼底成像；成像系统

英文摘要： A large variety of arteriovenous vessels distributing in human fundus reflecte hypertension,arteriosclerosis,rheumatism and other diseases.Fundus image can be used as an important credential in the study and diagnosis of diseases.Further,it can determine the seversity of other diseases.In addition, the development of portable armarium in minitype has high meaning to the spread of armarium in the countryside which safeguards the health of farmers and makes 3 farming carried out better. As a result, the research of eyeground imaging matches the requirement of healthy and stability society well. In this work a new technique able to achieve partial super resolution fundus image and partial high resolution three-dimensional shape is proposed applicable to different human eyes,using multiple lighting system ,partial super resolution imaging technique and partial high resolution three-dimensional shape measuring technique.The mutiple lighting system involves the illumination of the whole object, the illumination of the super resolution imaging area and the projecting of the fringe patterns. In the imaging optical system,fully taking into account the different optical properties of different human eyes and the displacement of the image produced by the human eye jitter,using digital adaptive optics technology, retinal visual cells can be distinguished by means of segmented aberration correction .Through post image processing,the partial super resolution fundus image and the partial three-dimensional shape of the fundus are achieved.

英文关键词： partial super-resolution;complexity illumination;adaptive optics;human eye-ground imaging;imaging system