基于磁性分子印迹固相萃取和电催化还原脱溴的四溴双酚A高选择性富集检测方法研究

项目名称： 基于磁性分子印迹固相萃取和电催化还原脱溴的四溴双酚A高选择性富集检测方法研究

项目编号： No.61501423

项目类型： 青年科学基金项目

立项/批准年度： 2016

项目学科： 无线电电子学、电信技术

项目作者： 王晋芬

作者单位： 国家纳米科学中心

项目金额： 20万元

中文摘要： 本项目面向水环境中痕量有毒有机污染物四溴双酚A的低浓度和高选择性在线检测需求，提出一种集成有磁性分子印迹固相萃取富集功能和电化学还原脱溴检测功能的痕量四溴双酚A检测方法。本项目通过研究基于微流控芯片的磁性分子印迹固相萃取界面构筑方法，改善传统固相萃取方法的再生性，获得一种高富集效率和可更新式的四溴双酚A富集方法；通过研究纳米复合材料的表界面特性、电催化还原脱溴机理，利用还原脱溴特性，提高检测的响应信号和特异性，获得四溴双酚A高选择性检测方法；结合基于微流控芯片的磁性分子印迹固相萃取和电催化还原脱溴检测，获得一种四溴双酚A的富集检测一体化微流控芯片，为水环境中四溴双酚A的准确、在线检测提供一种新的方法和途径。

中文关键词： 四溴双酚A；微流控芯片；磁性分子印迹固相萃取；电催化还原脱溴；微电子机械系统

英文摘要： According to the demand of low concentration and high selectivity for toxic tetrabromobisphenol A (TBBPA) in water environment, a detection method integrating magnetic molecularly imprinted solid-phase extraction (m-MISPE) preconcentration and electroreductive debromination determination was investigated. A construction method of m-MISPE based on microfluidic chip was investigated to improve the regeneration of traditional SPE method. A highly efficient and renewable preconcentration method of TBBPA was obtained. The surface and interface characteristic of nanomaterials and the electroreductive debromination mechanism were investigated to improve the response signal and selectivity. A highly selective TBBPA detection method was obtained. The m-MISPE preconcentration and the electroreductive debromination determination were integrating into microfluidic chip to apply accurate and on-line determination of TBBPA method in water environment.

英文关键词： tetrabromobisphenol A;microfluidic chip;magnetic molecularly imprinted solid-phase extraction;electroreductive debromination;Micro Electro-Mechanical System