A pandemic poses particular challenges to decision-making with regard to the types of decisions and geographic levels ranging from regional and national to international. As decisions should be underpinned by evidence, several steps are necessary: First, data collection in terms of time dimension as well as representativity with respect to all necessary geographical levels is of particular importance. Aspects such as data quality, data availability and data relevance must be considered. These data can be used to develop statistical, mathematical and decision-analytical models enabling prediction and simulation of the consequences of interventions. We especially discuss the role of data in the different models. With respect to reporting, transparent communication to different stakeholders is crucial. This includes methodological aspects (e.g. the choice of model type and input parameters), the availability, quality and role of the data, the definition of relevant outcomes and tradeoffs and dealing with uncertainty. In order to understand the results, statistical literacy should be better considered. Especially the understanding of risks is necessary for the general public and health policy decision makers. Finally, the results of these predictions and decision analyses can be used to reach decisions about interventions, which in turn have an immediate influence on the further course of the pandemic. A central aim of this paper is to incorporate aspects from different research backgrounds and review the relevant literature in order to improve and foster interdisciplinary cooperation.
翻译:在从区域和国家到国际的各类决定和地理层次的决策方面,大流行病对决策构成特殊的挑战,从区域到国家到国际的各类决定和地理层次,由于决定应以证据为基础,必须采取若干步骤:第一,在一切必要的地理层次上,从时间层面和代表性收集数据特别重要;必须顾及数据质量、数据提供情况和数据相关性等各个方面;这些数据可用于制定统计、数学和决策分析模型,以便能够预测和模拟干预措施的后果;我们特别讨论了数据在不同模式中的作用;在报告方面,与不同利益攸关方的透明沟通至关重要;这包括方法方面(例如选择模式类型和投入参数)、数据的可得性、质量和作用、相关结果和权衡的定义以及应对不确定性;为了了解结果,应更好地考虑统计知识普及问题;特别是,公众和卫生决策者必须了解风险;最后,这些预测和决策分析的结果可用于就干预措施作出决定,而这又对进一步推进大流行病进程产生直接影响。