We study the effects of physical distancing measures for the spread of COVID-19 in regional areas within British Columbia, using the reported cases of the five provincial Health Authorities. Building on the Bayesian epidemiological model of Anderson et al. (2020), we propose a hierarchical regional Bayesian model with time-varying regional parameters between March to December of 2020. In the absence of COVID-19 variants and vaccinations during this period, we examine the regionalized basic reproduction number, modelled prevalence, relative reduction in contact due to physical distancing, and proportion of anticipated cases that have been tested and reported. We observe significant differences between the regional and provincial-wide models and demonstrate the hierarchical regional model can better estimate regional prevalence, especially in rural regions. These results indicate that it can be useful to apply similar regional models to other parts of Canada or other countries.
翻译:我们利用五个省卫生当局报告的案例,对不列颠哥伦比亚省各地区COVID-19传播的物理偏移措施的影响进行研究。我们以Anderson等人(2020年)的Bayesian流行病学模型为基础,提出了2020年3月至12月之间具有时间变化的区域参数的Bayesian等级区域模型。由于在此期间没有COVID-19变量和接种疫苗,我们审查了区域化基本生殖数量、模拟流行率、身体偏移导致接触相对减少、以及已经测试和报告的预期病例比例。我们观察到区域和全省范围的模型之间存在巨大差异,并表明等级区域模型可以更好地估计区域流行率,特别是农村地区,这些结果表明,将类似的区域模型应用于加拿大其他地区或其他国家可能是有益的。