To consider model uncertainty in global Fr\'{e}chet regression and improve density response prediction, we propose a frequentist model averaging method. The weights are chosen by minimizing a cross-validation criterion based on Wasserstein distance. In the cases where all candidate models are misspecified, we prove that the corresponding model averaging estimator has asymptotic optimality, achieving the lowest possible Wasserstein distance. When there are correctly specified candidate models, we prove that our method asymptotically assigns all weights to the correctly specified models. Numerical results of extensive simulations and a real data analysis on intracerebral hemorrhage data strongly favour our method.
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