Prediction of diabetes and its various complications has been studied in a number of settings, but a comprehensive overview of problem setting for diabetes prediction and care management has not been addressed in the literature. In this document we seek to remedy this omission in literature with an encompassing overview of diabetes complication prediction as well as situating this problem in the context of real world healthcare management. We illustrate various problems encountered in real world clinical scenarios via our own experience with building and deploying such models. In this manuscript we illustrate a Machine Learning (ML) framework for addressing the problem of predicting Type 2 Diabetes Mellitus (T2DM) together with a solution for risk stratification, intervention and management. These ML models align with how physicians think about disease management and mitigation, which comprises these four steps: Identify, Stratify, Engage, Measure.
翻译:对糖尿病及其各种并发症的预测在一些环境中已经进行了研究,但文献中没有涉及糖尿病预测和护理管理问题设置的全面概述,在本文件中,我们力求纠正文献中的这一遗漏,全面概述糖尿病并发症预测,并将这一问题置于现实世界的保健管理背景下。我们通过我们自己在建立和部署此类模型方面的经验来说明在现实世界临床假想中遇到的各种问题。在本稿中,我们介绍了一个机器学习框架,用以处理预测2型糖尿病Mellitus(T2DM)的问题,并找出风险分级、干预和管理的解决办法。这些ML模型与医生如何思考疾病管理和缓解问题相一致,这包括这四个步骤:确定、调整、启用、措施。