项目名称: 网络成瘾患者内隐认知偏倚与事件相关电位及影像异常特征的相关性
项目编号: No.81471354
项目类型: 面上项目
立项/批准年度: 2015
项目学科: 医药、卫生
项目作者: 周振和
作者单位: 南京医科大学
项目金额: 70万元
中文摘要: 网络成瘾是一种严重的社会问题,应用内隐认知理论研究网络成瘾发病机制具有重要意义。申请者先前证实网络成瘾属于习惯与冲动控制障碍或与之相关的障碍,网络成瘾患者表现出大脑执行功能的缺陷,存在内隐认知偏倚。因此推测网络成瘾患者内隐认知偏倚在成瘾行为形成、发展以及预后起重要作用。探明网络成瘾内隐认知偏倚的神经机制对该病的病因、诊断、治疗以及预后的评价具有重要价值。本研究假设网络成瘾患者大脑中枢神经系统功能改变是网络成瘾行为发生、发展的生理基础,拟应用内隐联想测验实验范式同步进行事件相关电位和功能性磁共振成像试验,结合事件相关电位时间分辨率优势以及功能性磁共振成像的空间分辨率,系统研究网络成瘾患者内隐认知偏倚的事件相关电位以及神经影像学特征,探讨网络成瘾患者内隐认知偏倚与事件相关电位及影像异常特征的相关性,阐明网络成瘾发生的神经机制。研究结果可为网络成瘾的诊断以及防治提供理论和临床实验依据。
中文关键词: 网络成瘾;内隐认知偏倚;内隐联想测验;事件相关电位;磁共振成像
英文摘要: Internet addictive disorder is one of major social problems. It has significance to study Internet addictive disorder employing theory of implicit cognition. Previous studies had proved that Internet addictive disorder belongs to Impulse control disorders or related disorder, and patients who suffer from Internet addictive disorder present executive dysfunction and bias to Internet-related items. Therefore, it deduces that it is important to study complicit cognitive bias on Internet addictive disorder. The hypothesis of this research is that nervous system dysfunction is physiological mechanism in patients with Internet addictive disorder. The objective of this study is to investigate the association among complicit cognitive bias, abnormal Event-related potential and functional magnetic resonance imaging characters, and to identify neural mechanisms for Internet addictive disorder, by combining examination of Event-related potential and Functional magnetic resonance imaging under Implicit Association Test model. Findings would provide theory and clinical experiment evidence for Internet addictive disorder.
英文关键词: Internet addictive disorder;complicit cognitive bias;Implicit Association Test;Event-related potential;Functional magnetic resonance imaging