自动管电流调制CT辐射剂量与影像质量评价方法研究

项目名称： 自动管电流调制CT辐射剂量与影像质量评价方法研究

项目编号： No.11475047

项目类型： 面上项目

立项/批准年度： 2015

项目学科： 数理科学和化学

项目作者： 刘海宽

作者单位： 复旦大学

项目金额： 94万元

中文摘要： 医用X射线CT的辐射剂量与影像质量优化匹配问题是当今国内外辐射防护剂量学、医学影像学等相关学科领域共同关注的热点之一，自动管电流调制（ATCM）技术是低剂量医用X射线CT技术发展的主流方向。本项目主要针对ATCM工作模式下CT装置的辐射输出特性、受检者剂量以及影像质量评价这三个方面的问题，拟结合蒙卡模拟计算与现场测量方法，通过研发适用于ATCM工作模式下的CT剂量模体与图像质量模体，建立ATCM模式下CT辐射剂量输出与图像质量的准确评价方法；借助GPU蒙卡并行计算和数字化人体模型，建立大样本的受检者器官剂量与有效剂量与个体化的受检者扫描野内局部剂量分布的快速估算方法，并探讨基于器官的管电流调制技术在降低眼晶体剂量方面的应用。本项目研究结果可用于准确评价新的低剂量CT检查技术条件下的受检者剂量与影像质量，这对于对合理的降低CT受检者辐射剂量以及CT的辐射剂量与影像质量优化研究具有重要意义。

中文关键词： X射线CT；自动管电流调制；辐射剂量；影像质量评价；蒙特卡罗方法

英文摘要： X-ray CT radiation exposure to patient and its image quality have drawn international attention involving radiation protection and dosimetry,medical image et,al. Recently, Automatic Tube Current Modulation(ATCM) technic has been clinical widely used, which makes CT radiation and image quality an essential issue in the research erea. This project aims to explore new method to access the CT radiation exposure and image quality of ATCM technique. The major part of this project include the characteristic of tube current modulated CT output evaluation, patients dose estimation of ATCM and CT image quality appraision of ATCM. Both Monte Carlo simulation and and field measurements will be used to perform the project.New method of fast evulate CT radiation dose and image quality of ATCM will be established by developping new CT dose phantom and image quality test phantom. With Monte Carlo GPU parallel computing and digital human phantoms, organ dose and effective dose for large samples as well as individual specific local dose distribution in the scan erea could be fast estimated, and this project will also explore the organ-based tube current modulation technique in terms of reducing the eye lens dose.The results of this project can be used to accurately evaluate the dose and image quality of CT with new low-dose technology. This research project will help to promote research and application of the optimization of raidation dose and image quality of low-dose CT examination.

英文关键词： computed tomography;automatic tube current modulation;radiation dose;image quality evaluation;Monte Carlo method