树形表面活性剂/石墨烯纳米复合材料的组装及生物大分子检测

项目名称： 树形表面活性剂/石墨烯纳米复合材料的组装及生物大分子检测

项目编号： No.21205132

项目类型： 青年科学基金项目

立项/批准年度： 2013

项目学科： 分析化学

项目作者： 赵红

作者单位： 中国科学院大学

项目金额： 27万元

中文摘要： 石墨烯大的比表面积、高导电性和高电子传导速率使其在生物传感等领域具有十分广阔的应用前景。不同纳米材料的协同作用使纳米复合材料呈现出更好的光学、电学和催化活性，已成为前沿研究领域之一。在本申请中，我们将树形表面活性剂与纳米粒子/石墨烯纳米复合材料相结合，构建一种新型的生物大分子传感器。通过对表面活性剂分子结构的精确设计，合成一类性能优良的树形表面活性剂。通过研究树形表面活性剂形成纳米胶束的条件以及纳米胶束、纳米粒子在石墨烯表面的组装行为和尺寸效应，来制备性能优异的纳米胶束/纳米粒子/石墨烯纳米复合材料，从而实现对生物大分子（如葡萄糖氧化酶和酪蛋白等）的高选择性和高灵敏度检测。

中文关键词： 石墨烯；纳米复合材料；电化学传感器；生物分子；检测

英文摘要： Graphene has attracted strong scientific and technological interests in recent years. Its unique physicochemical properties (high surface area, excellent thermal and electric conductivity, and great mechanical strength) enable it with great potential applications in many areas such as biosensors and so on.The graphene-based hybrid nanocomposites may take advantage of the synergetic effects from different nanomaterials and provide enhanced performances in terms of optical, electronic, and catalytic properties, which has become one of the leading-edge research areas. In this project,nano-micelles of tree-type surfactant will be assembled on the surface of nanoparticles/graphene nanocomposites, thus a novel biomacromolecule sensor will be realized. A class of excellent tree-type surfactants will be synthesized through precise design of the structure of the surfactant molecules. To prepare nano-micelles/nanoparticles/graphite nanocomposite materials with excellent performance,formation conditions of nano-micelles by tree type surfactants, assembly behaviors of nano-micelles and naoparticles on the surface of the graphene and size effect of nanoparticles will be studied in details. Thus highly sensitive and selective detection of biomacromolecules such as glucose oxidation enzyme and casein will be realized.

英文关键词： Graphene；Composite nanomaterials；Electrochemical sensor；Biomolecular；Detection