超疏水微纳米阵列的制备及高灵敏表面增强拉曼散射分析研究

项目名称： 超疏水微纳米阵列的制备及高灵敏表面增强拉曼散射分析研究

项目编号： No.21275135

项目类型： 面上项目

立项/批准年度： 2013

项目学科： 数理科学和化学

项目作者： 李壮

作者单位： 中国科学院长春应用化学研究所

项目金额： 80万元

中文摘要： 申请者提出制备超疏水的表面增强拉曼散射（SERS）活性基底，为实现高灵敏的SERS检测提供基础。由于SERS实际检测到的探针分子仅分布在激光照射的微区约1-2平方微米内，超疏水基底能够限制探针分子溶液的铺展，将探针分子"锁定"在尽可能小的区域内，对降低检测限具有重要意义。申请者拟利用化学合成与组装方法制备超疏水微纳米结构；利用扫描探针显微镜纳米加工与纳米操纵技术，在超疏水表面构筑"纳米粒子亲水微区"；将以上两种微纳米结构用作SERS基底，研究拉曼激光照射微区内银、金等纳米粒子的尺寸、形状等对SERS的影响，探索SERS的增强机理；研究表面的疏水性质对SERS的影响，寻找水溶液液滴和超疏水表面间的接触角与SERS谱峰的增强因子之间的联系；实现有机污染物的高灵敏检测，探索利用拉曼光谱的指纹效应，不经分离直接从食品、水中检测特定有机污染物的可能性。

中文关键词： 超疏水；微纳米阵列；扫描探针显微镜；表面增强拉曼散射；分析

英文摘要： We proposed the preparation of superhydrophobic Surface-enhanced Raman Scattering (SERS) active substrates for high sensitive detection. The area irradiated by Raman laser is about 1-2 square micron in which the molecules could be detected. The superhydrophobic SERS substrates will restrict the spread of probe solution, so the probe molecules will be locked in a small area, which is very important for decreasing the detection limit. We proposed to fabricate superhydrophobic SERS substrates by two kinds of strategies. First, superhydrophobic SERS substrates were fabricated by chemical synthesis and assembly; second, by nanolithography and manipulation using Scanning Probe Microscopy (SPM), a small hydrophilic spot was obtained on the surface of superhydrophobic surface.These substrates will be utilized as SERS substrates to investigate how the size, shape and arrangement of silver，gold nanoparticles in laser irradiated area influence on the SERS effect, and the enhancement mechanism will be explored furtherly. The effect of hydrophobic properties of substrates to SERS will be studied, and some effort will be made for finding the relationship of SERS band enhancement factor and the contact angle between the water drop and the substrate. Using these superhydrophobic SERS active substrates, the high sensitive detec

英文关键词： Superhydrophobic；Micro-nanostructures；Scanning Probe Microscope (SPM)；Surface-enhanced Raman Scattering (SERS)；Analysis