有机刚性大环分子的可控自组装及相关纳米管的结构与功能研究

项目名称： 有机刚性大环分子的可控自组装及相关纳米管的结构与功能研究

项目编号： No.91227109

项目类型： 重大研究计划

立项/批准年度： 2013

项目学科： 有机化学

项目作者： 龚兵

作者单位： 北京师范大学

项目金额： 100万元

中文摘要： 基于有机合成的可控纳米孔通道的自组装和功能调控及其应用在国际上尚处于起步阶段，因而我国在这方面的研究与世界先进水平基本同步，预计未来5-10年在国际上会有一批具有重要影响的基础研究和应用方面的突破。本项目的实施，预计将会研发出多种具有特殊设计功能的有机纳米孔通道材料，阐明此类通道材料的可控自组装和在受限纳米空间条件下物质选择性输运的基本规律，为分子分离、纯化以及药物输送等广泛领域提供多种类多层次多功能的自组装纳米材料平台、技术支撑和理论基础，进一步提升我国在这一领域的创新能力和国际竞争能力，培养并造就一支高水平、稳定的研究队伍，将有利于推动我国相关新兴产业的发展。

中文关键词： 刚性大环；寡聚芳香胺；纳米管；自组装；离子通道

英文摘要： Fully functionalizable nano-pores and nano-channels fabricated via molecular self-assembly has been considered as a class of materials that holds great promise for a wide variety of applications. It is expected that fundamental breakthroughs in mechanistic studies and applications will be made in this filed in the coming years (most likely, in the next five to ten years). We propose to develop porous structures and the corresponding materials based on the directed self-assembly of shape-persistent macrocycles. New insights on the corresponding molecular self-assembly processes that are directed by multiple non-covalent interactions. A major object of this project is to gain better understandings on the processes involving mass transportation under nano-confinement. Progress made from the proposed studies will lay solid theoretical and experimental foundations for breakthroughs in the development of the next generation of technologies for applications including molecular separation/purification and drug delivery. Accomplishing the objectives of this project will greatly enhance our nation’s leading position both in basic research and related industries in this filed.

英文关键词： rigid macrocylcles；aromatic oligoamide；nanopores；self-assemble；ion channels