微流控芯片中电动非牛顿幂律流体的输运机理及实验研究

项目名称： 微流控芯片中电动非牛顿幂律流体的输运机理及实验研究

项目编号： No.11302095

项目类型： 青年科学基金项目

立项/批准年度： 2014

项目学科： 数理科学和化学

项目作者： 杨大勇

作者单位： 南昌大学

项目金额： 26万元

中文摘要： 微流控芯片是一种新型的微全分析系统，在生物医学、分析化学等领域具有广泛的应用前景。生物溶液的非牛顿幂律流体内部特性复杂，限制了微流控芯片在生物流体领域的应用。本项目以非牛顿幂律流体为研究对象，对微流控芯片中流场-电场-浓度场-温度场等多物理场耦合特性及流体输运规律进行研究。内容包括：对血液生物流体的流变特性进行分析和检测，完善非牛顿幂律流体的本构模型；采用有限元方法对微流控芯片中非牛顿幂律流体电动流进行直接耦合数值模拟，研究复杂结构微通道内非牛顿幂律流体流动的微观机理和宏观规律；研究非牛顿幂律流体输运系数和控制参数等对微流动的影响状况，揭示微流控芯片中非牛顿幂律流体流动的调控机理。对非牛顿幂律流体的电渗流速度进行实验检测，并将理论分析、数值模拟和实验结果进行对照，提出用于非牛顿幂律流体分析的微流控芯片结构和参数的优化设计方法，为微流控芯片内各种生物流体的精确操控与检测奠定理论和应用基础。

中文关键词： 微流控芯片；非牛顿幂律流体；电动流；数值模拟；实验研究

英文摘要： Microfluidic chip is a novel kind of micro total analytical system, which has broad application prospects in the field of biomedical, analytical chemistry, etc. The transport properties of non-Newtonian power-law fluid of the biological solution is complex in the internal characteristics, limiting the application of microfluidic chips in biological fluids. This project studies the flow- electric-heat-concentration multiphysics fields coupling characteristics and transport properties of the non-Newtonian power-law fluids in microfluidic chips. The main contents include: Rheological properties of blood biological fluid analysis and detection, and improve the constitutive model of the power-law non-Newtonian fluid; Direct coupling numerical simulation of the electrokinetic flow of the non-Newtonian power-law in microfluidic chips using finite element analysis, to understand the microscopic mechanism and macro flow rules of the non-Newtonian power-law in microchannels with complex structures. Study the effects of the non-Newtonian power law fluid transport coefficients and control parameters on the microflow, to reveal the regulation mechanism of the electrokinetic flow of non-Newtonian power-law fluids in microfluidic chips. Testing the electroosmotic flow rate of the non-Newtonian power-law fluid; and the results

英文关键词： Microfluidic chips；Non-Newtonian power-law fluids；Electrokinetic fluids；Numerical simulation；Experimental studies