Salen(M)功能化的手性多孔有机聚合物的合成及不对称催化性能研究

项目名称： Salen(M)功能化的手性多孔有机聚合物的合成及不对称催化性能研究

项目编号： No.21303205

项目类型： 青年科学基金项目

立项/批准年度： 2014

项目学科： 数理科学和化学

项目作者： 林祖金

作者单位： 中国科学院福建物质结构研究所

项目金额： 25万元

中文摘要： 多孔有机聚合物(POPs)具有稳定性高、比面积大、孔尺寸可调、孔表面易修饰等优点，因此在气体吸附与分离、催化等领域展现出了巨大的应用前景。均相手性Salen(M)催化剂在烯烃不对称环氧化、环氧化合物水解的动力学拆分等不对称催化表现出很高的催化活性和良好的对映体选择性，因而得到化学工作者的广泛研究。本项目拟选用手性Salen(M)催化剂为单体，设计合成孔尺寸可调的手性POPs材料。探索Salen(M)功能化的手性POPs材料在烯烃不对称环氧化、环氧化物水解动力学拆分等不对称催化的催化活性和对映体选择性。通过选择孔道尺寸合适的手性POPs材料，优化催化反应的条件，希望合成出易与产物分离、可循环利用、催化活性高和对映体选择性好的多相手性POPs催化剂。该项目的研究有助于降低手性Salen(M)催化剂的成本，对催化剂的工业应用具有重要的意义。本项目预期发表论文5-10篇，申请专利1-3件。

中文关键词： 多孔有机聚合物；异相催化；席夫碱；手性；不对称催化

英文摘要： Due to the highly thermal and chemical stability, high surface areas, fine-tunable pore sizes and surfaces, porous organic polymers (POPs) have been exploited for applications in gas adsorption and separation, heterogeneous catalysis. Homogeneous chiral metal/salen catalysts have received considerable attention because of their excellent asymmetric catalytic activities and selectivities in the asymmetric alkene epoxidation, asymmetric cyclopropanation, the hydrolytic kinetic resolution (HKR) of terminal epoxides and etc.. This project is planning to design and syntheses of a series of chiral POPs via direct incorporation of well-define asymmetric homogeneous metal/salen precatalysts. The pore sizes of POPs can easily be tuned via a linear change of the monomer in a given network topology. By examination the catalytic activities and selectivities of chiral POPs in the asymmetric alkene epoxidation, asymmetric cyclopropanation, epoxide ring-open reactions, and etc., we aim to develop a new generation of effective heterogeneous asymmetric catalysts with highly catalytic activity and excellent shape-, size-, chemo-, and enantioselective. In addition, the ability to easily recover and reuse such POP-based heterogeneous asymmetric catalysts is also highly desirable for reducing processing and waste disposal costs in l

英文关键词： Porous Organic Polymers；Heterogeneous Catalysis；salen；chiral；asymmetric catalysis