基于多模态神经信息和剂量学方法研究LTE电磁场暴露对人脑功能的影响

项目名称： 基于多模态神经信息和剂量学方法研究LTE电磁场暴露对人脑功能的影响

项目编号： No.61201066

项目类型： 青年科学基金项目

立项/批准年度： 2013

项目学科： 电子学与信息系统

项目作者： 吕彬

作者单位： 工业和信息化部电信研究院

项目金额： 26万元

中文摘要： 近年来，LTE(Long Term Evolution)作为新一代无线通信技术得到了迅速发展。我国提出的TD-LTE标准也已经在国内部分地区开通了实验网，并即将商用。在这一技术大规模使用之前，有必要从多角度对它进行电磁场健康效应的研究，从而在保证人民群众健康的同时，促进LTE相关产业顺利发展。 本研究将综合EEG、fMRI两种手段，应用脑功能连接分析技术和剂量学仿真计算来研究LTE电磁场暴露对脑功能的影响。在实验室可控环境中搭建LTE电磁照射平台，对脑部进行局部电磁照射实验。采集照射前后EEG、fMRI数据，分析脑功能状态的局部特征和脑区间网络连接情况。同时基于MRI图像分割头部组织，并建立头部解剖学数字模型，利用时域有限差分法分析各被试大脑整体及局部的电磁场能量吸收情况。最后，综合EEG、fMRI分析结果与电磁场剂量学结果，评估人脑受LTE电磁场照射后能量分布情况与脑功能激发状态的关系。

中文关键词： 电磁辐射；功能磁共振；脑电；电磁场剂量学；

英文摘要： In recent years, Long Term Evolution (LTE) has developed rapidly as the new generation of wireless telecommunication technology. As a technique proposed by China, experimental networks of TD-LTE have been deployed in some areas and will soon be available for commercial use. It is necessary to investigate the health effects of the electromagnetic fields (EMF) from different endpoints before any large-scale application. This work will not only protect the human health, but also promote the development of LTE-related industries. In this study, we will combine EEG and fMRI, brain connectivity methods as well as dosimetry to investigate the effects of LTE-related EMF on human brain function. We establish the LTE exposure platform to perform the local exposure experiment. The EEG and fMRI data are recorded from prior- and post- exposure. By multimodal analysis, we obtain the regional functional features and the connectivity performances of brain function. Meanwhile, we perform the segmentation based on MRI images to reconstruct the numerical head models. The finite-difference time-domain method is subsequently applied to evaluate the power absorption in each head model subjected to EMF exposures. At the end, we integrate the results from EEG/fMRI experiments and from dosimetry to investigate the relationship between

英文关键词： electromagnetic field exposure；fMRI；EEG；electromagnetic simulation；