基于微声学谐振腔的低检出限生物传感

项目名称： 基于微声学谐振腔的低检出限生物传感

项目编号： No.61271139

项目类型： 面上项目

立项/批准年度： 2013

项目学科： 无线电电子学、电信技术

项目作者： 李锋

作者单位： 中国科学院长春光学精密机械与物理研究所

项目金额： 65万元

中文摘要： 本研究将充分利用微声学谐振腔的能量局域效应，获得高Q值，为生物检测的低检出限、高灵敏度检测提供新途径；在粘弹性边界基础上，探讨谐振腔多模式的构建，以及被测液体的调制作用及其在生物检测中的物理意义；研究微声学谐振腔多模式对被测物密度、粘度、温度等参数进行解耦与识别的方法；给出微声学谐振腔传感器的灵敏度、品质因数的平衡点以及获得最佳检出限的途径；解决被测生物媒质的多参数表征、温度补偿等问题，实现生物分子的低检出限探测与识别。

中文关键词： 谐振腔；传感器；声子晶体；缺陷模式；

英文摘要： Theoritically, the membrane acoustic sensor can have extremly high sensitivity. However, the quality factor and precision of these acoustic sensor are low due to the attenuation and the influence of liquid . In order to obtain high sensitive and high precesion, the characters of multi-layer membrane with liquid loaded will be studied in this research. By investigating the evanescent field and energy flow, the trade off between Q factors and sensitivity will be optimized. The influence of thickness, density, viscosity of biolayer to the wave guide and enviromental temperature will be studied, thus these parameters can be measured simultaneously by using several resonating modes. Further more, the fabrications, the integration, excitation and measurement of the sensors will be studied. It is hoped that these study can provide a novel method, which satisfies the need for high precision bio sensing in home security and clinical applications.

英文关键词： resonator；sensor；phononic crystal；defect mode；