With more than 1.7 million COVID-19 deaths, identifying effective measures to prevent COVID-19 is a top priority. We developed a mathematical model to simulate the COVID-19 pandemic with digital contact tracing and testing strategies. The model uses a real-world social network generated from a high-resolution contact data set of 180 students. This model incorporates infectivity variations, test sensitivities, incubation period, and asymptomatic cases. We present a method to extend the weighted temporal social network and present simulations on a network of 5000 students. The purpose of this work is to investigate optimal quarantine rules and testing strategies with digital contact tracing. The results show that the traditional strategy of quarantining direct contacts reduces infections by less than 20% without sufficient testing. Periodic testing every 2 weeks without contact tracing reduces infections by less than 3%. A variety of strategies are discussed including testing second and third degree contacts and the pre-exposure notification system, which acts as a social radar warning users how far they are from COVID-19. The most effective strategy discussed in this work was combined the pre-exposure notification system with testing second and third degree contacts. This strategy reduces infections by 18.3% when 30% of the population uses the app, 45.2% when 50% of the population uses the app, 72.1% when 70% of the population uses the app, and 86.8% when 95% of the population uses the app. When simulating the model on an extended network of 5000 students, the results are similar with the contact tracing app reducing infections by up to 79%.
翻译:在170万COVID-19死亡超过170万人的情况下,确定防止COVID-19-19的有效措施是一项最优先事项。我们开发了一个数学模型,以数字接触追踪和测试战略来模拟COVID-19流行病。模型使用由180名学生组成的高分辨率接触数据集产生的真实世界社会网络。模型包含感染变异、测试敏感度、孵化期和无症状病例。我们提出了一个扩大加权时间社会网络和在5000名学生网络上进行模拟的方法。这项工作的目的是调查最佳检疫规则并用数字联系追踪测试战略。结果显示,终止直接接触的传统战略在没有进行充分测试的情况下,将感染减少不到20%。每两周定期测试一次,不进行接触的一组数据集将感染减少不到3%。讨论了各种战略,包括测试第二和第三级接触以及暴露前的通报系统。我们提出了一个方法,作为社会雷达警告用户在CVID-19的网络中,它们距离COVID-19的距离有多远。这项工作中讨论的最有效战略是将探索前通知系统与二级和第三层接触的测试系统结合起来,在没有进行充分检测的情况下,直接接触的减少感染人数不到20%。每两周一次检查时,使用50度接触时,这一战略将人口减少感染率使用18.3%,使用50 %的人口,然后将人口使用50 % 和25 % 的接触。