The growing demand for head magnetic resonance imaging (MRI) examinations, along with a global shortage of radiologists, has led to an increase in the time taken to report head MRI scans around the world. For many neurological conditions, this delay can result in increased morbidity and mortality. An automated triaging tool could reduce reporting times for abnormal examinations by identifying abnormalities at the time of imaging and prioritizing the reporting of these scans. In this work, we present a convolutional neural network for detecting clinically-relevant abnormalities in $\text{T}_2$-weighted head MRI scans. Using a validated neuroradiology report classifier, we generated a labelled dataset of 43,754 scans from two large UK hospitals for model training, and demonstrate accurate classification (area under the receiver operating curve (AUC) = 0.943) on a test set of 800 scans labelled by a team of neuroradiologists. Importantly, when trained on scans from only a single hospital the model generalized to scans from the other hospital ($\Delta$AUC $\leq$ 0.02). A simulation study demonstrated that our model would reduce the mean reporting time for abnormal examinations from 28 days to 14 days and from 9 days to 5 days at the two hospitals, demonstrating feasibility for use in a clinical triage environment.
翻译:对头磁共振成像(MRI)检查的需求不断增加,加上全球放射学家短缺,导致全世界报告主磁共振扫描所需的时间增加。对于许多神经系统条件而言,这种延迟可能导致发病率和死亡率上升。自动三角工具可以通过在成像时识别异常和优先报告这些扫描,减少异常检查的报告时间。在这项工作中,我们展示了一个动态神经神经网络,用于检测美元=T ⁇ 2美元重量级头部扫描中与临床有关的异常。我们使用一个经验证的神经放射学分类器,制作了一套有标签的43 754次扫描的数据集,来自两家大型英国医院进行模型培训,并展示准确的分类(接收器运行曲线下的区域=0.943),由一组神经放射学家标注的一组800次扫描。重要的是,当我们从一家单一医院扫描一个普通模型到另一家医院扫描的扫描时(Delta$$=leq2美元),我们制作了一套有标签的数据集,有43 75次扫描,从两天的模拟研究显示我们模型在正常环境检查时,从25天到25天进行。