A full Bayesian approach to the estimation of Vaccine Efficacy is presented, which is an improvement over the currently used exact method conditional on the total number of cases. As an example, we reconsider the statistical sections of the BioNTech/Pfizer protocol, which in 2020 has led to the first approved anti-Covid-19 vaccine.
翻译:对疫苗效率的估计采用了全面的巴耶斯方法,这比目前使用的以病例总数为条件的确切方法有所改进,例如,我们重新考虑BioNTEch/Pfizer协议的统计部分,该议定书在2020年导致首次批准反Covid-19疫苗。