Brain computer interfaces systems are controlled by users through neurophysiological input for a variety of applications including communication, environmental control, motor rehabilitation, and cognitive training. Although individuals with severe speech and physical impairment are the primary users of this technology, BCIs have emerged as a potential tool for broader populations, especially with regards to delivering cognitive training or interventions with neurofeedback. The goal of this study was to investigate the feasibility of using a BCI system with neurofeedback as an intervention for people with mild Alzheimer's disease. The study focused on visual attention and language since ad is often associated with functional impairments in language and reading. The study enrolled five adults with mild ad in a nine to thirteen week BCI EEG based neurofeedback intervention to improve attention and reading skills. Two participants completed intervention entirely. The remaining three participants could not complete the intervention phase because of restrictions related to covid. Pre and post assessment measures were used to assess reliability of outcome measures and generalization of treatment to functional reading, processing speed, attention, and working memory skills. Participants demonstrated steady improvement in most cognitive measures across experimental phases, although there was not a significant effect of NFB on most measures of attention. One subject demonstrated significantly significant improvement in letter cancellation during NFB. All participants with mild AD learned to operate a BCI system with training. Results have broad implications for the design and use of bci systems for participants with cognitive impairment. Preliminary evidence justifies implementing NFB-based cognitive measures in AD.
翻译:虽然严重言语和身体障碍者是这一技术的主要使用者,但BCI公司已成为广大民众的潜在工具,特别是在提供认知培训或神经反弹干预方面。这项研究的目的是调查使用带有神经退缩的BCI系统作为轻度阿尔茨海默氏病患者的干预手段的可行性。研究的重点是视觉关注和语言,因为广告往往与语言和阅读方面的功能障碍有关。研究在9至13周的BCI EEG神经回馈干预中招收了5名轻微广告的成年人,以提高关注和阅读技能。两名参与者完全完成了干预。其余3名参与者由于与阅读有关的限制而无法完成干预阶段。使用前和事后评估措施评估措施来评估结果的可靠性,以及治疗功能阅读、处理速度、注意力和工作记忆技能的普及。参与者在实验阶段中表现出了大多数认知措施的稳步改善,尽管基于神经回退缩的神经回退动干预措施在B公司最大程度上没有显著影响。