During the last two decades, a number of countries or cities established heat-health warning systems in order to alert public health authorities when some heat indicator exceeds a predetermined threshold. Different methods were considered to establish thresholds all over the world, each with its own strengths and weaknesses. The common ground is that current methods are based on exposure-response function estimates that can fail in many situations. The present paper aims at proposing several data-driven methods to establish thresholds using historical data of health issues and environmental indicators. The proposed methods are model-based regression trees (MOB), multivariate adaptive regression splines (MARS), the patient rule-induction method (PRIM) and adaptive index models (AIM). These methods focus on finding relevant splits in the association between indicators and the health outcome but do it in different fashions. A simulation study and a real-world case study hereby compare the discussed methods. Results show that proposed methods are better at predicting adverse days than current thresholds and benchmark methods. The results nonetheless suggest that PRIM is overall the more reliable method with low variability of results according to the scenario or case.
翻译:在过去二十年中,一些国家或城市建立了热卫生预警系统,以便在一些热指标超过预定阈值时提醒公共卫生当局注意公共卫生当局,考虑采用不同的方法,确定世界各地的阈值,每个阈值都有自己的优势和弱点。共同点是,目前的方法基于暴露-反应功能估计,在许多情况下可能失败。本文件的目的是提出若干数据驱动的方法,利用健康问题和环境指标的历史数据确定阈值。提议的方法有:基于模型的回归树(MOB)、多变量的适应性回归样条、病人规则引入方法和适应性指数模型(AIM)。这些方法侧重于在指标与健康结果之间找到相关的差异,但以不同的方式进行。模拟研究和现实世界案例研究在此比较讨论的方法。结果显示,拟议的方法比目前的阈值和基准方法更能预测不利的日子。但结果表明,TRIM总体上是比较可靠的方法,根据假设或案例,结果的变异性较低。