纳米修饰与3D打印联用技术在医用材料中的应用

项目名称： 纳米修饰与3D打印联用技术在医用材料中的应用

项目编号： No.21461015

项目类型： 地区科学基金项目

立项/批准年度： 2015

项目学科： 无机化学

项目作者： 王小磊

作者单位： 南昌大学

项目金额： 45万元

中文摘要： 3D打印技术可在短时间内精确构筑复杂的仿生结构，非常适用于医用器件的个性化生产。然而，目前可实际应用的医用3D原料有限、且表面性能难以满足生物医用材料的实际使用需求。申请人于09年在国际上率先提出在复杂结构的基底表面，修饰高生物相容性无机纳米阵列的技术方案，非常适用于3D打印领域。现计划联合纳米修饰与3D打印两项前沿技术，通过在3D打印器件表面负载功能型纳米材料，显著提升成品的生物相容性、抗菌性、疏水能力等关键性能参数。重点研究该项联用技术在快速制备人造牙齿、人造骨骼等植入材料的应用价值。本项目具有原始创新性和长远发展前景，可填补我国在个性化生产纳米医用材料领域的空白，并产生可观的经济效益。申请人在相关领域申请专利5项，获省部级奖励两次，七篇代表性论文平均影响因子达8.2，在国内同行中位居前列。

中文关键词： 纳米复合材料；纳米材料；纳米结构

英文摘要： 3D printing technology is capable to construct complex bionic structure precisely in a short time, and is thus ideal for personalized production of medical devices. However, at this stage, the available 3D printing biomedical raw materials are very limited, and their surface properties are also insufficient for the practical requirements. In 2009, the appliant proposed a reliable approach to modify complex structured substrate with high biocompatible inorganic nanoarrays, which is an ideal strategy for 3D printing technology. Herein, the appliant planed to start a joint research project between nano-modification and 3D printing. This joint technique is based on the actual needs of the common biomedical materials, especially artificial teeth and bone tissue materials. By modifying the surfaces of 3D printing products with intelligent nanomaterials, some key performance parameters of biomedical devices, such as biocompatibility, antibacterial activity and hydrophobic ability, can be significantly improved. Incorporated with original innovation and long-term development potential, this technology can fill in the domestic gap in the field of rapid manufacturing personalized intelligent biomedical nano-materials, and generate considerable economic benefits. The average impact factor of the appliant's first author selected publication is 8.2.He also owns 5 patents and 2 provincial awards, representing the leading level in domestic counterparts.

英文关键词： nanocomposite;nanomaterials;nanostructure