项目名称: 新疆维吾尔族,哈萨克族淀粉样脑血管病相关性脑出血的研究
项目编号: No.30860292
项目类型: 地区科学基金项目
立项/批准年度: 2009
项目学科: 金属学与金属工艺
项目作者: 更·党木仁加甫
作者单位: 新疆医科大学
项目金额: 25万元
中文摘要: 淀粉样脑血管病相关性脑出血(CAAH)是淀粉样脑血管病(cerebral amyloid angiopathy, CAA)最常见和最严重的并发症, 是老年人非外伤、非高血压性脑出血,特别是复发性脑出血的一个重要病因,占所有老年人脑出血病例的12%~15%。新疆是一个地域辽阔,多民族聚集的地方,其中维吾尔族人口940 余万,哈萨克族人口140 余万,又是一个脑血管病的高发区,近年来,国内外学者围绕着淀粉样脑血管病开展了大量的流行病学研究,但有关新疆维吾尔族,哈萨克族淀粉样脑血管病相关性脑出血的研究未见报道,开展新疆少数民族CAAH 的研究在学术研究和社会经济等各个方面都具有现实和深远的意义。因此本研究从新疆的民族和地域特点出发,初步了解新疆少数民族CAA 相关性脑出血的部分流行病学特点,同时研究其病理、影像、和临床特征,解决该病诊断率低的问题,在以上研究的基础上制订合理有效的治疗措施。
中文关键词: 淀粉样脑血管病;脑出血;维吾尔族;哈萨克族
英文摘要: Cerebral amyloid angiopathy hemorrhage (CAAH) is considered the most common and severe complication of cerebral amyloid angiopathy (CAA). It is an important cause of spontaneous hemorrhage in aged people which accounted for 12~15% of all intracerebral hemorrhage (ICH). With population aging, the patients suffered CAAH will become more and more. Xinjiang is a developing province with high incidence of cerebrovascular diseases, and which has 9.4 millions uighur and 1.4 millions Kazakh population. Although many research related to CAA and CAAH have been reported all around the world, the epidemiology of this special entity in uighur and Kazakh is still unknown, which will profit both to anthropological understanding and government policy making. The purpose of this study is to investigate the epidemiology of CAAH in Xinjiang, and the features in CAAH on images, pathological test and in clinical settings. The data of this study will be the best evidence for diagnosis and management of this disease.
英文关键词: Cerebral Amyloid Angiopathy;Intracerebral Hemorrhage;Uyghur;Kazakh