类水滑石纳米片/手性大分子电化学传感器的构建及分子识别研究

项目名称： 类水滑石纳米片/手性大分子电化学传感器的构建及分子识别研究

项目编号： No.21271127

项目类型： 面上项目

立项/批准年度： 2013

项目学科： 数理科学和化学

项目作者： 丁亚萍

作者单位： 上海大学

项目金额： 80万元

中文摘要： 手性是自然界的本质属性之一。手性识别已成为无机功能材料领域的研究前沿和热点。本项目拟将纳米片层组装技术与电化学方法相结合，将手性大分子的区域选择性及手性识别优势与电化学传感的简便快速、灵敏高效等优点相结合，开展水滑石纳米片/手性大分子新型电化学传感器的构建及分子识别研究。通过功能设计，采用电荷相同、半径相近的过渡金属离子同晶取代水滑石结构中Mg2+、A13+，制备电活性好的多元类水滑石前驱体；用新型剥层技术制备带有正电荷的水滑石纳米片，并借助现代仪器手段表征产物的结构和性能；利用多元类水滑石纳米片上高密度电荷、丰富的氢键位点及酸碱反应活性，将优选的匹配手性大分子组装到纳米片上，获得无机/有机手性复合材料；在电活性基底上构建出系列性能优异、结构稳定的手性电化学传感器件，以实现不同类型对映体的手性识别和高灵敏传感。该研究不仅具有传感器件上的创新，而且在手性分离和检测方面具有广阔的应用前景。

中文关键词： 类水滑石；纳米片；复合材料；电化学传感器；手性识别

英文摘要： Chirality is one of the essential attribute of nature and has attracted a lot of attention from various areas. With the development of technology, chiral recognition has become the frontier and hot spots of research in the field of inorganic functional materials. Our research tends to combine nano-layer assembly technology with electrochemistry methods. At the meantime, making a combination of the advantages of the region selectivity of chiral macromolecules as well as chiral recognition and the characteristics of electrochemical sensors, such as simplicity, speed, sensitivity and high efficiency, etc. Based on the premise, we try to conduct the research on the construction of hydrotalcite-like nanosheets/chiral macromolecules electrochemical sensor as well as the study of molecule recognition. By functional design, the Mg2+ and Al3+ in the molecular structure of hydrotalcite will be replaced by the transition metal, whose charge is the same with Mg2+ and Al3+and radius are close with substituted elements. By this, we can require the precursor of multi-class hydrotalcite with perfect electrical activity. After that, to prepare the nanosheets of hydrotalcite with positive charge by the new type of stripping layer technology, and analyzing the structure and properties of as-prepared nanosheets with modern instrume

英文关键词： Layered Double-Hydroxide；Nanosheets；Compound materials；electrochemical sensor；chiral recognition