稀土纳米材料电化学发光性能及生物传感研究

项目名称： 稀土纳米材料电化学发光性能及生物传感研究

项目编号： No.21465013

项目类型： 地区科学基金项目

立项/批准年度： 2015

项目学科： 高分子科学

项目作者： 黄海平

作者单位： 江西理工大学

项目金额： 50万元

中文摘要： 本项目主要研究稀土纳米材料的电化学发光（ECL）性能及其在生物传感领域的应用。首先通过各种液相化学方法制备具有形貌和大小可控的稀土纳米材料；并对所制备的纳米材料进行表征，分析其元素组成，价态结构，光学性质等。测试稀土纳米材料的电化学行为，构建其直接电子传递模型。详细研究稀土纳米材料的电化学发光性能。分析不同稀土元素、不同扫描电位和不同共反应物对稀土ECL 发射光强度的影响；探讨稀土ECL 发光机理；寻求稀土ECL 最大发光强度所需的实验条件。利用稀土材料良好的生物相容性和ECL 性能，构建新型高效的稀土ECL 生物传感器。通过对传感器与目标分析物反应前后的ECL 发光强度的变化，实现对目标物的检测。本研究项目不仅对研制新型电化学发光材料具有重要意义，同时为开辟稀土资源有效利用的新途径、扩展其应用范围、把地区资源优势变为经济优势提供重要的科研价值。

中文关键词： 稀土；纳米材料；制备；电化学发光；生物传感器

英文摘要： This project was planed to study the electrochemiluminescence (ECL) property of rare earth nanomaterial and its applications in the field of biosensor. The morphology and size controlled rare earth nanomaterials would firstly be prepared via chemical liquid routes, and characterized by various techniques so as to analyze their elemental components, valence configurations and optical properties. Then, the electrochemical behavior of the prepared materials would be investigated in order to construct the model of the direct electron transfer (DET). For the purpose of fully studying the ECL property of rare earth nanomaterials, various experimental parameters, such as the different rare elements, scan potentials and co-reactants, would be employed to observe their effects on the ECL emission intensity. The ECL mechanism of rare earth and the optimistic conditions for the maximum emission intensity were schemed to be investigated. Via the utilization of ECL property, the novel and high-effected rare earth ECL biosensors were proposed to be fabricated. The ECL changes before and after the interaction between the probe and target analyte were proposed to be detected to achieve the target detection. This project plays an important role in the development of novel ECL material. In the meantime, it provides the solid scientific values to open the new high-effected utilization of rare earth, to expend rare earth's application scopes, so as to change the regional resource advantages into economic advantages.

英文关键词： Rare earth;Nanomaterial;Preparation;Electrochemiluminescence;Biosensor