表面功能调控的石墨烯三维组装体构建生物传感

项目名称： 表面功能调控的石墨烯三维组装体构建生物传感

项目编号： No.21205059

项目类型： 青年科学基金项目

立项/批准年度： 2013

项目学科： 分析化学

项目作者： 王凤彬

作者单位： 南京大学

项目金额： 28万元

中文摘要： 石墨烯具有诸多独特的性质，在电子、能源、催化和传感等领域有广泛的应用前景。但石墨烯片层间的强π堆积效应将使其诸多性能下降。为此，本项目拟制备具有稳定三维结构的石墨烯组装体，并探索其在生物电分析和传感中的应用。首先以模板自组装法、水热法和有机凝胶-溶胶法等制备具有稳定三维空间结构的石墨烯组装体，并结合化学修饰技术在石墨烯表面连接上不同类型的功能团；随后，将三维结构石墨烯组装体作为酶和蛋白质等生物分子固定化的基底，研究固定化生物分子电化学和电催化性能等；在此基础上，构建基于三维多孔石墨烯组装体的电化学生物传感器。

中文关键词： 三维石墨烯；金属-石墨烯复合物；电催化；聚赖氨酸-石墨烯；生物传感器

英文摘要： Graphene has many unique properties and a broad prospect in electronics, energy, catalysis and sensing and other fields. But strong stacking effect between graphene layers led to decreased performance such as specific surface. Therefore, this project aims to prepare stable three-dimensional assembly structure of graphene, and to explore its application in biological analysis and sensing. First，we will prepare stable three-dimensional assembly structure of graphene by self-assembly method, hydrothermal method and organic gel-sol method, and change the property of graphene surface by connection of different types of functional group; Subsequently, enzymes and proteins will be immobilized on the three-dimensional assembly structure of graphene. We will study the electrochemical and electrocatalytic performance from biomolecules immobilized on the different interface. On this basis, construct the electrochemical biosensor based on the three-dimensional porous graphene assembly.

英文关键词： three dimensional graphene；metal–graphene nanocomposite；electrocatalysis；poly-L-lysine-graphene hybrid；biosensor