纳米材料增敏的高性能分子印迹膜电化学传感器的研制及其在环境激素检测中的应用

项目名称： 纳米材料增敏的高性能分子印迹膜电化学传感器的研制及其在环境激素检测中的应用

项目编号： No.21277105

项目类型： 面上项目

立项/批准年度： 2013

项目学科： 环境科学、安全科学

项目作者： 赵发琼

作者单位： 武汉大学

项目金额： 80万元

中文摘要： 基于分子印迹的电化学传感器具有良好的发展前景，但目前尚存在传质速度慢、灵敏度低等问题。本项目拟采用集聚合、成膜、掺杂于一步的电聚合方法，并通过聚合单体纳米材料功能化、印迹基底纳米化、不同单体共聚以及调控电聚合参数等，研制纳米材料增敏的新型分子印迹膜传感器。具体拟以纳米贵金属负载的含巯化合物为功能单体，以纳米贵金属修饰电极为基底，制备多级纳米放大的复合印迹传感膜；在有机、无机物功能化的纳米碳表面电聚合，获取具高稳定性和导电性的网络结构印迹膜；用超声电沉积法制备碳纳米管-离子液体负载的具高催化活性的纳米合金，再在此基底上进行单或双单体电聚合印迹。由此提高印迹膜的印迹容量、传质速度、选择性和灵敏度。采用多种手段研究复合印迹膜的结构性能，探讨纳米材料的增敏机制和膜响应机理。进而研制实用性强的高性能分子印迹膜电化学传感器，建立某些典型环境激素的高灵敏检测方法。这将有力地推动分子印迹技术的应用与发展。

中文关键词： 纳米材料；分子印迹聚合物；电化学传感器；环境激素；

英文摘要： The molecular imprinted film-based electrochemical sensor(MIES) has great application and developing potential, but it has disadvantages of low sensitivity or slow mass-transfer rate. In this project, novel MIESs with high performance will be fabricated by electrochemical polymerization, which can combine polymerization, coating and doping into one step. We intend to improve the property of MIES through using nano-material functioned monomer, nano-material based substrate, co-polymerization of different monomer and optimizing polymerization conditions. To be specific, we will fabricate MIES using polymerizable mercpto-monomer loaded on nano-noble metals and nano-noble metal substrate immobilized on electrode surface; prepare MIES with high stability and conductivity and net-like structure through imprinting on the surface of multi-walled carbon nanotubes modified by organic, inorganic compound or ionic liquid; construct MIES by adopting substrate of catalytic nano-alloy coated carbon nanotube -ionic liquid composite and co-polymerizaion of two monomers. As the nano-materials have large area/mass ratio, high conductivity and electrocatalysis,two monomers can present better interaction with the template molecule,through these methods, the imprinted capacity, mass-transfer rate, selectivity and sensitivity of the o

英文关键词： nanomaterial；molecularly imprinted polymer；electrochemical sensor；environmental hormones；