基于强化预处理+厌氧消化的抗生素菌渣资源化处理处置基础研究

项目名称： 基于强化预处理+厌氧消化的抗生素菌渣资源化处理处置基础研究

项目编号： No.51478160

项目类型： 面上项目

立项/批准年度： 2015

项目学科： 其他

项目作者： 李再兴

作者单位： 河北科技大学

项目金额： 80万元

中文摘要： 抗生素菌渣是一种特殊的危险废物，其合理、安全处置是目前制药企业亟待解决的难题。本项目通过分析不同抗生素菌渣的基础理化性质和污染特征，明确抗生素菌渣的共性和差异性；在此基础上以典型抗生素菌渣为研究对象，开展菌渣物化方法与嗜热溶胞菌耦合强化预处理破胞试验，探究其作用机制；此后，开展菌渣破解液厌氧消化基础特性研究，包括：菌渣破解液对厌氧消化的抑制效应及成因、零价铁及天然有机质强化菌渣破解液厌氧消化效能等，构建菌渣破解液厌氧消化ADM模型、微生物增殖动力学模型、生物质降解动力学模型和工艺参数优化控制模型等，结合反应器内微生物群落变化分析与监控，提出厌氧消化系统高效运行调控策略；最后，结合厌氧消化后沼渣好氧堆肥试验，对菌渣处理处置全过程的环境安全性进行评价；同时开展抗生素残留全生命周期分析，明晰其降解途径及环境归趋；通过以上研究，为抗生素菌渣的高效、安全、资源化处理处置提供基础理论支持和技术参考。

中文关键词： 抗生素菌渣；厌氧消化；强化预处理；基础理论；资源化

英文摘要： Antibiotics bacteria residue is a kind of special hazardous waste, and its reasonable and safe treatment and disposal is a key issue for pharmaceutical companies. In this project, the common and different characteristics of antibiotics bacteria residues would be determined by analyzing and comparing their physical-chemical characteristics and contamination properties. Based on this, representative antibiotic bacteria residues would be chosen, and enhanced pretreatment of these antibiotic bacteria residues would be carried out for bacteria lysing, using some physical-chemical processes and thermophilic lysis bacteria. The mechanisms of bacteria lysing would be investigated during the coupling enhanced pretreatment processes. Then anaerobic digestion of lysis products would be studied systematically after pretreatment of antibiotics bacteria residues, including: (1) the inhibitory effect and its causes; (2) anaerobic digestion performance enhanced by zero-valent iron reduction or adding natural organic matter; (3) anaerobic digestion model of anaerobic digestion, dynamic model of microbial proliferation and biomass degradation, and optimal control model of operational parameters; (4) the changes in microbial community. Moreover, the regulatory strategies would be suggested to achieve the efficient performance of anaerobic digestion. After anaerobic digestion, the aerobic composting would be employed as a disposal for obtained biogas residues. The environmental safety would be evaluated during the whole treatment and disposal processing of antibiotics bacteria residue mentioned above. In addition, full life-cycle of antibiotic residues would be analyzed, to clarify the degradation pathway and environmental fate of antibiotic residues. The achievements of this project would provide the theoretical and technical support for the efficient, safe and resourceful treatment and disposal of antibiotic bacterial residues.

英文关键词： antibiotics bacteria residue;anaerobic digestion;enhanced pretreatment;fundamental theory;resource utilization