In epidemiological studies, very often, evaluators obtain measurements of disease outcomes for study participants. In this paper, we propose a two-stage procedure for detecting outlier evaluators. In the first stage, a regression model is fitted to obtain the evaluators' effects. The outlier evaluators are considered as those with different effects compared with the normal evaluators. In the second stage, stepwise hypothesis testings are performed to detect outlier evaluators. The true positive rate and true negative rate of the proposed procedure are assessed in a simulation study. We apply the proposed method to detect potential outlier audiologists among the audiologists who measured hearing threshold levels of the participants in the Audiology Assessment Arm of the Conservation of Hearing Study, which is an epidemiological study for examining risk factors of hearing loss.
翻译:在流行病学研究中,评价人员往往为研究参与者获取疾病结果的测量结果;在本文件中,我们建议采用两阶段程序来检测外部评价人员; 在第一阶段,为取得评价人员的效果而设置了一个回归模型; 将外部评价人员视为与正常评价人员相比具有不同效果者; 在第二阶段,进行分步骤的假设测试,以检测外部评价人员; 在模拟研究中评估拟议程序的真正正率和真实负率; 我们采用拟议方法,在计量听力评估体系参与者听力阈值的听力学家中发现潜在的外部听力学家; 保存听力研究的听力评估体系是用于审查听力损失风险因素的流行病学研究。