人类记忆过程：概念启动与熟悉性的神经机制

项目名称： 人类记忆过程：概念启动与熟悉性的神经机制

项目编号： No.31271078

项目类型： 面上项目

立项/批准年度： 2013

项目学科： 医药、卫生

项目作者： 郭春彦

作者单位： 首都师范大学

项目金额： 86万元

中文摘要： 本项目以图片、汉字词为基本材料，制作不同类型的视觉刺激，即以被试的主观评定确定视觉刺激意义水平、以不同基本材料重新组合视觉刺激，以及利用错误记忆（DRM）范式生成'诱饵'词等方式，采用"学习-再认"范式，研究概念启动与熟悉性的神经机制。项目将采用行为实验、ERP实验技术、ERP+fMRI技术的方法，借助适合概念启动与熟悉性研究的多种实验设计，系统探讨：1）概念启动与熟悉性各自的神经机制，以及再认记忆中概念启动对熟悉性的影响；2）整体中部分概念（形）的重组对熟悉性神经机制的影响；3）由概念启动产生的错误的熟悉感对再认判断熟悉性的影响。本项目旨在探讨概念启动与熟悉性的神经机制，以及二者在脑区的重叠和相互作用。我们期待，通过对二者之间的神经关系，以及概念启动在各种条件下对熟悉性贡献这一新视角的探讨，进一步揭示内隐记忆与外显记忆的神经关系，以及内隐记忆对外显记忆贡献的神经机制。

中文关键词： 记忆；概念启动；熟悉性；事件相关电位；重组

英文摘要： This research will implement study-recognition paradigm to identify the neural mechanism of conceptual priming and familiarity. Based on pictures, Chinese characters, and words as basic materials, the researcher manufacture three different types of visual stimulants: stimulants with different meaning levels which depend on participants' evaluation, rearranged stimulants with different basic materials, and'lure words 'which are generated by DRM paradigm. By using multiple experimental designs and technologies, including behavioral experiment, ERP experimental technique, and ERP+fMRI technique, this research will systematically investigate following issues: 1) the neural mechanism for conceptual priming and for familiarity, and how conceptual priming influences familiarity in recognition memory; 2) the effect of portion conception（shape） rearranged on neural mechanism of familiarity; and 3) how false familiarity which emerges in conceptual priming impacts re-recognition judgment. Except investigating the neural mechanism of conceptual priming and familiarity, this research will also develop their overlaps in brain regions and interactions based on the experimental result. From this new perspective of how conceptual priming contributes to familiarity under different situations, and the neural relations between them

英文关键词： memory；conceptual priming；familiarity；event-related potential；rearranged