介体催化强化Cr(VI)生物还原机理及其调控策略研究

项目名称： 介体催化强化Cr(VI)生物还原机理及其调控策略研究

项目编号： No.51208170

项目类型： 青年科学基金项目

立项/批准年度： 2013

项目学科： 建筑环境与结构工程学科

项目作者： 廉静

作者单位： 河北科技大学

项目金额： 25万元

中文摘要： 项目针对重金属生物处理技术转化速率低、耗时长的问题，基于氧化还原介体催化强化污染物厌氧生物转化的研究热点和前期研究的基础，以典型重金属Cr(VI)为模型化合物，以介体调控电子传递为核心，构建氧化还原介体催化强化Cr(VI)生物还原的实验体系，开展如下研究：1）分离、筛选高效的Cr(VI)降解菌株，考察和优化菌株对Cr(VI)生物还原过程的影响因素；2）优化、筛选不同结构/类似结构的高效介体，建立相应的特性表征体系；3）从电化学、酶学和生物代谢等多角度展开研究，阐明介体催化强化Cr(VI)生物还原的作用机理；4）解读介体结构和催化效果之间的关系，构建和验证介体调控电子传递的构-效模型；5）优化反应器关键调控因素，探究各调控因素对反应器效能影响的规律，建立Cr(VI)生物转化技术调控策略。本项目的研究将拓展重金属污染生物转化研究的内涵，具有重要的理论意义、较强的学术前沿性和广阔的应用前景。

中文关键词： 六价铬；生物还原；氧化还原介体；调控机理；功能载体

英文摘要： Since chemical detoxification of metal-contaminated water is generally very expensive and often results in secondary effects on the environment, the cost-effective and eco-friendly biological treatment has attracted more interests. However, the biological treatment generally takes a long time to complete the reduction process. Based on above questions and the previous research results of the accelerating effect of redox mediators on the transformation of pollutions, the project is to explore the mechanism and regulatory strategies of hexavalent chromium bioreduction enhanced by redox mediators. The main contents of this project include the following: 1)The efficient Cr(VI) reduction microorganisms are isolated, screened and identified, and the influencing factors of the reduction process by these microorganisms are optimized; 2)redox mediators with different/similarity structure are screened and optimized, and the characterization systems of redox mediators are established; 3)the mechanism of Cr(VI) bioreduction enhanced by redox mediators is elucidated from electrochemistry, enzymology and metabolization; 4)the relationship between the structure of the redox mediators and their accelerating effects is explored, and the model of electron transfer with redox mediators is established and verified;5)the main contro

英文关键词： Hexavalent chromium；Bioreduction；Redox mediators；Regulatory mechanisms；Functional biocarrier