基于不对称双齿配体的BODIPY类荧光分子的构筑及其发光性质研究

项目名称： 基于不对称双齿配体的BODIPY类荧光分子的构筑及其发光性质研究

项目编号： No.21301085

项目类型： 青年科学基金项目

立项/批准年度： 2014

项目学科： 数理科学和化学

项目作者： 刘志鹏

作者单位： 聊城大学

项目金额： 25万元

中文摘要： 以硼氟吡咯（BODIPY）为代表的有机硼氟配合物由于具有高的摩尔消光系数和量子产率，以及波长范围可调的优势已经被广泛应用于荧光检测、生物分子的荧光标记以及光捕集系统等领域。目前限制BODIPY类荧光分子应用的两个主要缺点是其斯托克斯位移较小(7-15 nm)以及固态荧光猝灭严重。因此，设计合成具有大斯托克斯位移和强的固态荧光的BODIPY类荧光分子的研究备受关注。本项目将针对BODIPY类荧光分子斯托克斯位移小以及固态荧光猝灭严重的缺点，拟利用双齿配体不对称化的设计策略，通过苯并唑类与异吲哚啉，吡啶，喹啉等含氮杂环化合物或苯酚/萘酚，萘酰亚胺等含氧化合物杂化共轭，设计合成一系列同时具有大的斯托克斯位移以及较强固态荧光的BODIPY类荧光分子，系统研究它们的构效关系，为新型BODIPY类荧光分子的设计合成提供有效的理论支持。促进BODIPY化学的发展。

中文关键词： 不对称双齿配体；硼氟配合物；荧光；大的斯托克斯位移；固态发光

英文摘要： Organic fluorine-boron complexes, with BODIPYs (boron diprromethene and its derivatives) as the example, are a family of best-known fluorescent dyes with some excellent properties. Their high absorption coefficients and quantum yields, and tunable emission from visible light to near infrared allow BODIPYs to be applied in the field of fluorescence sensing and imaging,and light harvest.Unfortunately, most of BODIPYs diplay rather low Stokes shift of typically 7-15 nm, which would results in self-absorption of their emitted photons. Moreover, BODIPYs often show non fluorescence in the solid state due to aggregation-induced fluorescence quenching. Therefore, great efforts have been paid to the design and synthesis of BODIPYs with large Stokes shift and intense fluorescence in the solid state in recent years. To address this need, in this project, we present that desymmetrization of bidentate ligand should be a potential strategy for the construction of BODIPYs with large Stokes shift and intense fluorescence in the solid state. By conjugating of benzoles with isoindolin, pyridine, quinoline, phenol, naphthol or naphthalimide derivatives, a seires of novel BODIPYs with large Stokes shift and intense fluorescence in the solid state will be synthesized. The relationship between the structure and the optical properties

英文关键词： desymmetrized bidentate ligands；Boron-fluorine complex；fluorescent；large Stokes shift；emissive in the solid state