杂冠醚类荧光探针分子的表面自组装膜制备及对汞离子的传感研究

项目名称： 杂冠醚类荧光探针分子的表面自组装膜制备及对汞离子的传感研究

项目编号： No.21203244

项目类型： 青年科学基金项目

立项/批准年度： 2013

项目学科： 物理化学

项目作者： 袁群惠

作者单位： 中国科学院新疆理化技术研究所

项目金额： 25万元

中文摘要： 汞离子难于自然降解、易于生物富集，对人和自然界的危害巨大。本项目将结合申请人在表面自组装、单分子水平表界面化学反应方面的研究基础，开展汞离子响应型荧光探针分子表面自组装的研究工作。拟选用一系列以杂冠醚为识别基团、以富电子π体系为发色基团、对汞离子具有高选择性传感响应的荧光探针分子为结构基元，利用表面自组装技术、扫描隧道显微术等技术手段，研究溶剂、发色基团、分子取代基等因素对于自组装过程的影响，并在单分子水平上获得对于主客体识别、光致电子转移等微观过程的深入认识。此外，探索组装后荧光探针分子保持对于汞离子活性响应的条件，以期通过较为简单的方法有效地实现荧光探针分子的表面固定化，为开发基于荧光探针分子的汞离子传感器提供理论线索和实验依据。

中文关键词： 重金属离子；荧光探针；扫描隧道显微术；碳量子点；

英文摘要： Mercury ions normally go through bio-accumulation ways rather than biodegradable ways in ecological system, bringing huge damage to people and natural environment. Herein, based on my previous studies on surface/interface self-assembly and single molecular reactions, we plan to study the surface self-assembly of fluorescent molecules with mercury ion sensitivity. By selecting fluorescent molecules with azacrown as recognition moiety for mercury ion while π conjugation as chromophore, the factors that affect surface self-assembled structures, such as the type of the solvent, the chromophore and the substituted group in fluorescent molecules will be studied with scanning tunneling microscope (STM). Mechanisms such as recognition between host-guest molecules and photo induced electron transfer process will be studied at single molecular level. We also plan to explore the conditions that keep fluorescent molecules sensitive to mercury ions in surface assemblies, and achieve immobilized film of fluorescent probes by simple and effective approaches. This project will provide clues for the development of fluorescence sensors for mercury ion detection in both theoretical and practical ways.

英文关键词： heavy metal ion；fluorescence probe；scanning tunneling microscopy；carbon quantum dot；