项目名称: 非抛弃式重金属离子电化学微流控芯片平台的构建
项目编号: No.21305078
项目类型: 青年科学基金项目
立项/批准年度: 2014
项目学科: 数理科学和化学
项目作者: 陈朝贵
作者单位: 山东省科学院
项目金额: 25万元
中文摘要: 重金属离子检测一直是环境监测领域的研究重点,建立高灵敏,高准确,便携式的重金属离子传感平台,对于维护环境安全和人类健康等方面具有重要的意义。本项目利用在芯片上集成多种不同材质的微电极,构筑高集成的电化学传感单元用于灵敏的重金属离子的传感分析。基于芯片微结构的设计,发展同待测溶液不直接接触的稳定的芯片参比电极体系以及工作电极原位修饰和更新技术,提高电化学微流控检测芯片中工作和参比电极的稳定性和重复使用性能。该研究有利于改变目前大部分电化学芯片电极表面修饰困难,无法进行物理更新,容易损坏,稳定性差,只能抛弃性使用的现状,为最终构建可稳定长期使用的电化学微流控检测设备提供研究基础。
中文关键词: 微流体;微流控芯片;电化学;双极电极;在线分析
英文摘要: Due to the severe risk to human health and environmental safety, heavy metal ions assays have been attracted more attention in the field of the environmental monitoring. Accordingly, exploring portable, high-sensitivity, high accuracy sensing platform is urgently needed. In this project, a variety of microelectrodes using different materials are chosen to be integrated on a single chip, which can be acted as the electrochemical (EC) sensing unit for the highly sensitive detection of heavy metal ions. To improve the stability of reference electrodes, we intend to design the chip microstructure as the ions channel to avoid the direct contact with the analyze solution. Moreover, to obtain the renewable surface of working electrode (WE), "in-situ" modification of WE is employed. It can resolve some significant issues occurred on most EC chips (such as poor stability, subject to damage and not be physically renewed) and provide the theoretical and experimental supports for building a stable, long-term electrochemical microfluidic analysis.
英文关键词: microfluidic;microchip;electrochemical;bipolar electrode;on-line analysis