金属离子识别的荧光传感器可控制备与应用研究

项目名称： 金属离子识别的荧光传感器可控制备与应用研究

项目编号： No.21272293

项目类型： 面上项目

立项/批准年度： 2013

项目学科： 数理科学和化学

项目作者： 秦波

作者单位： 重庆大学

项目金额： 80万元

中文摘要： 碱和碱土金属、过渡金属和重金属广泛地存在于自然界中,人类的重大疾病和环境污染与这些金属阳离子有着密切地联系。当前,利用新材料、新方法和新工艺检测金属阳离子的种类和含量，对生命科学、医学和环境科学具有重要的意义。本项目借助有机合成和高分子聚合方法，以芳香折叠大环分子为基础，可控制备新型荧光分子传感器，对金属阳离子具有离子识别功能和开关性能，并构建荧光薄膜，实现离子在线荧光检测系统。探索阳离子识别与孔径、配位点等因素的关系，研发荧光传感器光控、溶致等开关特性，揭示金属阳离子识别的荧光检测机制，为荧光薄膜在线定性和定量检测物质奠定基础。

中文关键词： 吡啶酮；荧光；识别；笼架结构；电化学

英文摘要： Alkali，alkaline earth, transition and heavy metals can be abundantly found in the nature world. Studies showed that fatal disease and environmental pollution were closely related to metal cations. In this regards, the development of novel materials, method and technologies which could tell the species of the metal cations as well as quantitatively measure those cations is of great significance to life science, medicine and environmental science and has received increasingly attentions. Employing the organic synthesis and polymerization of foldamer-based circular aromatic amides, this project was designed to develop novel fluorescence chemosensors and fluorescence film materials with metal cation recognition and on-line detection application. It includes investigating the relationship between cation recognition and the cavity size and coordination site of the macrocycles, exploring fluorescent sensor with 'on-off' light control characteristics, unveiling the fluorescence detection mechanism of metal cations and constructing on-line cation detection system.

英文关键词： Pyridinone；Fluorescence；Recognition；Cage-frame Structure；Electrochemistry