项目名称: 基于高分子单晶的人工纳米马达的研究
项目编号: No.21304064
项目类型: 青年科学基金项目
立项/批准年度: 2014
项目学科: 数理科学和化学
项目作者: 董彬
作者单位: 苏州大学
项目金额: 26万元
中文摘要: 在自然界中存在的基于催化反应的生物纳米马达的启发下,利用纳米构造手段,人们发展出了能够在燃料推进下自主运动,并且可以在生物医学方面找到应用的人工马达。但是由于受到构造方法的限制,目前人工马达的研究还没有解决大批量生产以及实现可降解功能等对于其在生物医学方面的应用很关键的问题。在本项目中,我们提出以生物可降解高分子和纳米粒子为基本构筑单元,通过自下而上的方法将两者组装起来,从而发展出适合大批量生产的基于高分子单晶的人工纳米马达。另外,通过对高分子单晶材料的选择,高分子结晶过程的控制以及不同类型纳米粒子的引入,我们将可以实现具有催化、自主运动、货物装载及输运、传感以及可降解等多种功能的人工纳米马达的构筑。此项目的开展,对于推动人工纳米马达在生物医学方面的应用有积极的意义。
中文关键词: 高分子单晶;纳米马达;纳米粒子;;
英文摘要: Inspired by biological nanomotors, scientists have developed man-made nanomotors using nanofabrication method, which can move autonomously, propelled by a fuel and is capable of performing different complex tasks in biomedical applications. Due to the limitation in the fabrication method, researches in man-made motor haven't achieved mass production and biodegradability, which are the crucial steps towards its biomedical applications. In this project, we primarily use biodegradable polymer and nanoparticle as the building block to fabricate a man-made nanomotor based on polymer single crystal through bottom up strategy, which is suitable for mass production. By properly selecting the functional polymeric material for polymer single crystal, carefully controlling the polymer crystallization process and introducing different types of nanoparticles, we will be able to achieve a nanomotor that possess multi-functionalities, including catalysis, autonomous movement, cargo transportation, sensing and degradability. Current project will promote the development of man-made nanomotor in biomedical applications.
英文关键词: polymer single crystal;nanomotor;nanoparticle;;