基于四重氢键的超分子组装体及其功能化研究 （一）

项目名称： 基于四重氢键的超分子组装体及其功能化研究 （一）

项目编号： No.91227106

项目类型： 重大研究计划

立项/批准年度： 2013

项目学科： 有机化学

项目作者： 王乐勇

作者单位： 南京大学

项目金额： 75万元

中文摘要： 四重氢键是目前构筑超分子组装体和超分子聚合物最引人注目的超分子作用力之一。本申请项目拟基于四重氢键构筑的各种超分子作用基元为平台，展开以下三个方面的工作：1）开发简单且精致的模型来深入探索超分子聚合过程中的环链平衡机理，实现环链分布的高度可控，发展超分子聚合物研究中环链平衡理论架构；2）以四重氢键构筑基元为核心，通过多种超分子力的正交自组装，协同构筑具有可调控性能的超分子器件，如动态索烃、轮烷和笼状主体等；3）自主开发各种具有光电响应的功能基团桥联的UPy基元，组装成具有高度环境响应的“智能”超分子聚合物材料、自修复材料和仿生材料等。

中文关键词： 分子识别；分子自组装；超分子凝胶；超分子聚合物；超分子囊泡

英文摘要： Quadruple hydrogen bond is one of the most attractive supramolecular interactions which is usually employed to fabricate supramolecular aggregates and supramolecular polymers. We plan to take various supramolecular building blocks with quadruple hydrogen bonding recognition sites as platform, to develop the following three parts of researches: 1) We try to develop some simple but exquisite model to explore the ring-chain mechanism in supramolecular polymerization process, and finally realize the highly controllable distribution of ring-chain equilibrium. 2) Based on the quadruple hydrogen bonded building blocks, we will construct some supramolecular device, such as dynamic catenanes, rotaxanes and cage-like hosts through orthogonal self-assembly of multiple weak interactions. 3) Various photo- or electric-responsible functional group bridged UPy monomers would be synthesized, which would be further to self-assemble to environment responsible intelligent supramolecular polymers, self-healing materials and biomaterials.

英文关键词： Molecular Recognition；Molecular self-assembly；Supramolecular gels；Supramolecular polymers；Supramolecular vesicles