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A PhD studentship position is open for the fall semester 2020 in Dr. Zhiyong Cheng's lab (molecular metabolism and metabolic diseases) at the University of Florida. The chosen candidate will be supported by a full scholarship.
Dr. Cheng's lab seeks to understand the molecular mechanism of metabolic diseases (i.e., obesity and type 2 diabetes), with the goal of developing mechanism-based strategies for early diagnose and treatment of the diseases. Specifically, we are studying the cellular mechanism of adipocyte formation and expansion during obesity development, i.e., how FoxO1 and autophagy regulate adipogenesis and beiging of white adipose tissue [Cheng (2019) Trends in Endocrinololgy & Metabolism; Zhang (2018) Nature Reviews Endocrinology; Altshuler-Keylin (2017) Science Signaling). We collaborate with nano-medicine experts to develop nano-carriers to deliver drugs to treat obesity and metabolic syndrome. Another project ongoing in the lab is to study the epigenetic mechanism of diabetes progression, particularly focusing on DNA methylation [Cheng (2018) Journal of Nutritional Biochemistry; Davegårdh (2018) Molecular Metabolism). This is a translational research program, where we use cell culture for in vitro mechanistic study, and recruit obese individuals to examine the potential of epigenetic markers to diagnose early-stage prediabetes and assess the effect of lifestyle intervention.
The University of Florida is one of renowned universities in the US (#34 National Universities; #7 Top Public Schools according to the US News). Dr. Cheng is committed to the academic success of students in his lab, which is enhanced by his education and training experience at renowned universities (Peking University, the University of Michigan, and Harvard University Medical School). Under Dr. Cheng's supervision, the graduate students in his lab have been prepared as outstanding research scholars (e.g., postdoctoral researchers at Harvard University, and Columbia University) or teaching scholars (e.g., Houston Memorial Scholarship recipient for teaching excellence) per their career goals.
Applications are invited from those who hold a M.S. in biological sciences (e.g., biochemistry, molecular/cell biology, or a related field). Research experience in studying adipocytes, adipose tissue, and mouse models, is considered as a plus; so are peer-reviewed publications in international journals. Interested applicants should send their materials (CV, personal statement, GRE, TOEFL or IELTS, and GPA information) to Dr. Cheng at z.cheng@ufl.edu.
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