Optimal governance and implementation of vaccination programs to contain the COVID-19 pandemic

Once a viable vaccine for SARS-CoV-2 has been identified, vaccination uptake will determine our success in containing the COVID-19 pandemic. We argue that game theory and social network models should be used to guide decisions pertaining to vaccination programs for the best possible results. In the months following the introduction of vaccines, their availability and the human resources needed to run the vaccination programs will likely be scarce in many countries. Vaccine hesitancy can also be expected from some sections of the general public. We emphasize that decision making under uncertainty and imperfect information, and with only conditionally optimal outcomes, is a unique forte of established game theoretic modelling. Therefore, we can use this approach to obtain the best framework for modelling and simulating vaccination prioritisation and uptake that will be readily available to inform important policy decisions for the optimal control of the COVID-19 pandemic.