项目名称: 基于纳米力学的超声生物组织定征的理论和方法研究
项目编号: No.11274166
项目类型: 面上项目
立项/批准年度: 2013
项目学科: 数理科学和化学
项目作者: 刘晓宙
作者单位: 南京大学
项目金额: 80万元
中文摘要: 生物组织的超声定征研究近年来成为国际声学界研究的热点,它能揭示声波在各向异性的生物组织中的声传播规律及物理机制,因此是一个具有很强应用背景的基础性的研究课题。本项目拟采用纳米力学的理论研究超声在生物组织中的声传播,揭示生物组织非连续,非均质和多尺度的特征,建立有效的纳米力学的物理模型来解释声波在生物组织中传播的实验结果;利用纳米力学的参量来表征正常和病变组织,为定量,无损超声组织定征开辟一条新的途径,对这些问题的深入研究将有助于我们更深入地理解超声在生物组织中声参量变化的物理本质,促进超声诊断技术的进一步发展。
中文关键词: 纳米力学;微结构;生物组织;医学超声;组织定征
英文摘要: Ultrasonic tissue characterization has become an international hot topic in acoustic research in recent years,which can reveal the law of sound propagation and physical mechanism in anisotropical biological tissues, therefore it is a basic research with strong background in applications.In this project,the nanomechanics will be used to study the sound propagation in biological tissue, which will reveale the non-continuous,non-homogeneous and multi-scale characteristics of the biological tissues.We will make a nanomechanics physical model to explain the experimental results of sound propagation in biological tissues,and use the nanomechanics parameters to characterize the normal and diseased tissues, which will pave a new way to quantitative, nondestructive ultrasonic characterization of biological tissues. The study will help us to deep understand the nature of the change of the sound parameters of ultrasonics in biological tissues and promote the further development of ultrasound technology.
英文关键词: nanomechanics;micostructure;biological tissue;biomedical ultrasonics;tissue characterization