模糊配体衍生的低价锕系金属有机化合物的合成、结构及反应性研究

项目名称： 模糊配体衍生的低价锕系金属有机化合物的合成、结构及反应性研究

项目编号： No.21472013

项目类型： 面上项目

立项/批准年度： 2015

项目学科： 数理科学和化学

项目作者： 自国甫

作者单位： 北京师范大学

项目金额： 85万元

中文摘要： 由于锕系金属有机化合物在医药、化工及有机合成等领域具有广阔的应用前景，从而成为金属有机化学的前沿研究课题。到目前为止，对模糊配体衍生的低价锕系金属有机化合物的研究很少，还处于起步阶段，而锕系金属有机化合物又具有独特的磁性及反应性能。因此，开展对模糊配体衍生的锕系金属有机化合物的研究无疑具有重要的科学意义和潜在的应用价值。 本项目拟设计并合成出一系列模糊配体衍生的低价锕系金属有机化合物，并将其应用于小分子的活化反应，进行反应性能测试。通过磁性研究揭示其金属离子与模糊配体之间的电子作用关系，并将借助分子计算与模拟，对其反应性能进行探讨，研究其电子结构与反应性能之间的关系，为这类化合物在医药、化工及有机合成化学方面的潜在应用提供理论依据。同时，为了比较低价锕系金属有机化合物的反应性能，本项目也将在IVB族低价金属有机化合物方面做部分研究工作。

中文关键词： 锕系金属有机化合物；低价态；模糊配体；合成；反应性

英文摘要： The organoactinide complexes have received increasing attention because of their potential use in many fields such as medicine, chemical engineering, and organic synthesis, which makes it become one of the most significant research fields in organometallic chemistry. So far, low-valent organoactinide complexes with redox non-innocent ligands have been reported rarely, and this research work is at the beginning. According to their special properties in magnetism and reactivity, carrying out the research work in low-valent organoactinide complexes with redox non-innocent ligands is a desirable goal, which is not only in academic study but also in industry. A series of low-valent organoactinide complexes with redox non-innocent ligands would be designed and prepared, and their use in activation of small molecules would be studied. The electron interaction between actinide ion and redox non-innocent ligand would be investigated by magnetic susceptibility studies, and their reactivity would be further investigated by computational studies. A relationship between the electronic structure and reactivity would be established, which would provide an academic theory for their potential application in medicine, chemical engineering, and organic synthesis. For comparison, the group 4 organometallic complexes with redox non-innocent ligands would be included in this proposal.

英文关键词： Organoactinide complex;Low-valent;Redox non-innocent ligand;Synthesis;Reactivity