Cell 近期热门论文精选 | 导读推荐

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即可阅读来自 BioArt、生物探索的论文解读与评述。

陈玲玲团队揭示环形RNA在天然免疫过程中的重要功能

论文标题：Structure and degradation of circular RNAs regulate PKR activation in innate immunity

作者：Chu-Xiao Liu, Xiang Li, Fang Nan, Shan Jiang, Xiang Gao, Si-Kun Guo, Wei Xue, Yange Cui, Kaige Dong, Huihua Ding, Bo Qu, Zhaocai Zhou, Nan Shen, Li Yang, Ling-Ling Chen

期刊：Cell

发表时间：2019/04/25

猴子如何做决策？杏仁核——决策模拟中枢

论文标题：Primate Amygdala Neurons Simulate Decision Processes of Social Partners

作者：Fabian Grabenhorst, Raymundo Báez-Mendoza, Wilfried Genest, Gustavo Deco, Wolfram Schultz

期刊：Cell

发表时间：2019/04/11

担心变胖？这个基因评分系统，可以帮你准确预测风险

论文标题：Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood

作者：Amit V. Khera 15, Mark Chaffin 15, Kaitlin H. Wade, Sohail Zahid, Joseph Brancale, Rui Xia, Marina Distefano, Ozlem Senol-Cosar, Mary E. Haas, Alexander Bick, Krishna G. Aragam, Eric S. Lander, George Davey Smith, Heather Mason-Suares, Myriam Fornage, Matthew Lebo, Nicholas J. Timpson, Lee M. Kaplan, Sekar Kathiresan

期刊：Cell

发表时间：2019/04/18

抑制性染色质如何调控基因的转录？

论文标题：Promoter-Intrinsic and Local Chromatin Features Determine Gene Repression in LADs

作者：Christ Leemans, Marloes C.H. van der Zwalm, Laura Brueckner, Ludo Pagie, Joris van Arensbergen, Bas van Steensel

期刊：Cell

发表时间：2019/04/11

自噬领域再次开疆拓土：全新UIM-UDS互作模式参与自噬通路

论文标题：ATG8-Binding UIM Proteins Define a New Class of Autophagy Adaptors and Receptors

作者：Richard S. Marshall, Zhihua Hua, Sujina Mali, Fionn McLoughlin, Richard D.Vierstra

期刊：Cell

发表时间：2019/04/04

PD-1/L1为什么会无效？两篇研究揭秘免疫治疗耐药性

论文标题：Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory

作者：Mauro Poggio, Tianyi Hu, Chien-Chun Pai, Brandon Chu, Cassandra D. Belair, Anthony Chang, Elizabeth Montabana, Ursula E. Lang, Qi Fu, Lawrence Fong, Robert Blelloch

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期刊：Cell

发表时间：2019/04/04

利用线粒体进行人细胞谱系示踪

论文标题：Lineage Tracing in Humans Enabled by Mitochondrial Mutations and Single-Cell Genomics

作者：Leif S. Ludwig, Caleb A. Lareau, Jacob C. Ulirsch, Elena Christian, Christoph Muus, Lauren H. Li, Karin Pelka, Will Ge, Yaara Oren, Alison Brack, Travis Law, Christopher Rodman, Jonathan H. Chen, Genevieve M. Boland, Nir Hacohen, Orit Rozenblatt-Rosen, Martin J. Aryee, Jason D. Buenrostro, Aviv Regev Vijay G. Sankaran

期刊：Cell

发表时间：2019/03/07

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